Calmodulin inhibitors trigger the proteolytic processing of membrane type-1 matrix metalloproteinase, but not its shedding in glioblastoma cells

Biochemical Journal

Volumn 359, Issue 2, 2001, Pages 325-333

  Annabi, B ^a   Pilorget, A ^a   Bousquet Gagnon, N ^a   Gingras, D ^a   Beliveau R ^a  

^a UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

Author keywords

Actin cytoskeleton; Cell migration; Glioma; MT1 MMP; TIMP 2

Indexed keywords

CELLS; CYTOLOGY; ENZYMES; TISSUE;

PROTEOLYSIS;

BIOLOGICAL MEMBRANES;

CALMODULIN INHIBITOR; CONCANAVALIN A; CYTOCHALASIN D; GELATINASE A; MARIMASTAT; MATRIX METALLOPROTEINASE; MEMBRANE PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ARTICLE; CELL MIGRATION; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVATION; GLIOBLASTOMA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; REGULATORY MECHANISM;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CALMODULIN; COS CELLS; DNA, COMPLEMENTARY; ENZYME ACTIVATION; ENZYME PRECURSORS; GELATINASES; GLIOBLASTOMA; HUMANS; MATRIX METALLOPROTEINASES, MEMBRANE-ASSOCIATED; METALLOENDOPEPTIDASES; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TRIFLUOPERAZINE; TUMOR CELLS, CULTURED;

EID: 0035886927     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3590325     Document Type: Article

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