Identification of a neurite outgrowth-promoting motif within the alternatively spliced region of human tenascin-C

Journal of Neuroscience

Volumn 21, Issue 18, 2001, Pages 7215-7225

  Meiners, Sally ^a   Nur E Kamal, Mohammed S A ^a   Mercado, Mary Lynn T ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Alternatively spliced region; FN III repeat; Neurite outgrowth; Site directed modifications; Synthetic peptide; Tenascin C

Indexed keywords

ANTIBODY; FIBRONECTIN; LAMININ; PROTEOCHONDROITIN SULFATE; RECOMBINANT PROTEIN; SYNTHETIC PEPTIDE; TENASCIN;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; EMBRYO; GRANULE CELL; GROWTH REGULATION; NERVE FIBER GROWTH; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

EID: 0035885087     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-18-07215.2001     Document Type: Article

References (47)

1. The short amino acid sequence Pro-His-Ser-Arg-Asn in human fibronectin enhances cell-adhesive function
2. Cell- and heparin-binding domains of the hexabrachion arm identified by tenascin expression proteins
3. Expression of tenascin in the developing and adult cerebellar cortex
4. Distribution and function of tenascin during cranial neural crest development in the chick
5. Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1
6. Identification of a key integrin-binding sequence in VCAM-1 homologous to the LDV active site in fibronectin
7. Cytotactin and its proteoglycan ligand mark structural and functional boundaries in somatosensory cortex of the early postnatal mouse
8. Regeneration of adult axons in white matter tracts of the central nervous system
9. Up-regulation of astrocyte-derived tenascin-C correlates with neurite outgrowth in the rat dentate gyrus after unilateral entorhinal cortex lesion
10. Distinct effects of recombinant tenascin domains on neuronal cell adhesion, growth cone guidance, and neuronal polarity
11. Tenascin, laminin, and fibronectin produced by cultured cells
12. A neurite outgrowth-inhibitory proteoglycan expressed during development is similar to that isolated from adult brain after isomorphic injury
13. Chondroitin sulfate proteoglycan and tenascin in the wounded adult mouse neostriatum in vitro: Dopamine neuron attachment and process outgrowth
14. Human tenascin gene. Structure of the 5′-region, identification, and characterization of the transcription regulatory sequences
15. Tenascin-C contains distinct adhesive, anti-adhesive, and neurite outgrowth promoting sites for neurons
16. Tenascin-C synthesis and influence on axon growth during rat cortical development
17. Cytotactin, an extracellular matrix protein of neural and non-neural tissues that mediates glia-neuron interaction
18. Fatal bilateral chylothorax in mice lacking the integrin alpha9betal
19. Tenascin Mr 220 000 isoform expression correlates with corneal cell migration
20. The minimal essential sequence for a major cell type-specific adhesion site (CS1) within the alternatively spliced type III connecting segment domain of fibronectin is leucine-aspartic acid-valine
21. Structure of a fibronectin type III domain from tenascin-C by MAD analysis of the selenomethionyl protein
22. J1/tenascin in substrate-bound and soluble form displays contrary effects on neurite outgrowth
23. Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes
24. Long and short splice variants of human tenascin differentially regulate neurite outgrowth
25. Tenascin-C contains domains that independently regulate neurite outgrowth and neurite guidance
26. Neurite outgrowth promotion by the alternatively spliced region of tenascin-C is influenced by cell type specific binding
27. Identification of a novel recognition sequence for the integrin alpha 4 beta 1 in the COOH-terminal heparin-binding domain of fibronectin
28. Fibronectin type III5 repeat contains a novel cell adhesion sequence. KLDAPT, which binds activated alpha4betal and alpha4beta7 integrins
29. The GTPase-activating NF1 fragment of 91 amino acids reverses v-Ha-Ras-induced malignant phenotype
30. Repeated intracerebroventricular administration of beta-amyloid(25-35) to rats decreases muscarinic receptors in cerebral cortex
31. Selective labeling of embryonic neurons cultured on astrocyte monolayers with 5(6)-carboxyfluorescein diacetate (CFDA)
32. Separate cell binding sites within cytotactin/tenascin differentially promote neurite out-growth
33. Putative inhibitory extracellular matrix molecules at the dorsal root entry zone of the spinal cord during development and after root and sciatic nerve lesions
34. Localization during development of alternatively spliced forms of cytotactin mRNA by in situ hybridization
35. Incorporation of heparin-binding peptides into fibrin gels enhances neurite extension: An example of designer matrices in tissue engineering
36. Laminin A chain synthetic peptide which supports neurite outgrowth
37. Myelin-associated glycoprotein in myelin and expressed by Schwann cells inhibits axonal regeneration and branching
38. Human tenascin: Primary structure, pre-mRNA splicing patterns and localization of the epitopes recognized by two monoclonal antibodies
39. Sulfated proteoglycans in astroglial barriers inhibit neurite outgrowth in vitro
40. Boundaries defined by adhesion molecules during development of the cerebral cortex: The J1/tenascin glycoprotein in the mouse somatosensory cortical barrel field
41. The primary structure of the alpha 4 subunit of VLA-4: Homology to other integrins and a possible cell-cell adhesion function
42. The in situ localization of tenascin splice variants and thrombospondin 2 mRNA in the avian embryo
43. The integrin receptor alpha 8 beta 1 mediates interactions of embryonic chick motor and sensory neurons with tenascin-C
44. The integrin alpha 9 beta 1 mediates cell attachment to a non-RGD site in the third fibronectin type III repeat of tenascin
45. Identification of the ligand binding site for the integrin a9b1 in the third fibronectin type III repeat of tenascin-C
46. Tenascin-C expression and axonal sprouting following injury to the spinal dorsal columns in the adult rat
47. Degradation of chondroitin sulfate proteoglycan enhances the neurite-promoting potential of spinal cord tissue