Expression of a peptide epitope of the colonic mucin MUC2 in precursor lesions to gastric carcinoma

European Journal of Cancer Prevention

Volumn 5, Issue 4, 1996, Pages 287-295

  Filipe, M I ^a   Linehan, J M ^a   Durrant, L G ^b   Price, M R ^c   Smeeton, N C ^a   Pathak, S ^a   Swallow, D M ^d  

^a GUY S HOSPITAL   (United Kingdom)

^b NOTTINGHAM CITY HOSPITAL   (United Kingdom)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Dysplasia; Gastrc carcinoma; Intestinal metaplasia; MUC2; Mucin

Indexed keywords

EPITOPE; MUCIN;

ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; DYSPLASIA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; METAPLASIA; PRIORITY JOURNAL; PROGNOSIS; STOMACH CARCINOMA;

ANTIBODIES, MONOCLONAL; EPITOPES; GASTRIC MUCOSA; HUMANS; IMMUNOHISTOCHEMISTRY; MUCINS; NEOPLASM PROTEINS; PEPTIDES; PRECANCEROUS CONDITIONS; STOMACH NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 0029803587     PISSN: 09598278     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008469-199608000-00009     Document Type: Article

References (31)

1. Audie J, Janin A, Porchet N, Copin M, Gosselin B, Aubert J (1993). Expression of human mucin genes in respiratory, digestive and reproductive tracts ascertained by in situ hybridization. J Histochem Cytochem 41: 1479-85.
2. Bobek LA, Tsai H, Biesbrock AR, Levine MJ (1993). Molecular cloning, sequence, and specificity of expression of the gene encoding the low molecular weight human salivary mucin (MUC7). J Biol Chem 268: 20563-9.
3. Carrato C, Balague C, de Bolos C et al (1994). Differential apomucin expression in normal and neoplastic human gastrointestinal tissues. Gastroenterology 107: 160-72.
4. Chang S-K, Dohrman A, Basbaum C et al (1994). Localization of mucin (MUC2 and MUC3) messenger RNA and peptide expression in human normal intestine and colon cancer. Gastroenterology 107: 28-36.
5. Chambers JA, Hollingsworth MA, Trezise AE, Harris A (1994). Developmental expression of mucin genes MUC1 and MUC2. J Cell Sci 107: 413-24.
6. Correa P (1988). A human model of gastric carcinogenesis. Cancer Res 48: 3554-60.
7. Correa P, Fox J, Fontham E, Ruiz B, Lin Y, Zavala D (1990). Helicobacter pylori and gastric carcinoma: serum antibody prevalence in populations with contrasting cancer risks. Cancer 66: 2569-74.
8. CRC Fact Sheet (1990). Cancer Research Campaign Press, London.
9. Devine PL, McGuckin MA, Birrell GW et al (1993). Monoclonal antibodies reacting with the MUC2 mucin core protein. Br J Cancer 67: 1182-8.
10. Durrant L, Jacobs E, Price M (1994). Production of monoclonal antibodies recognising the peptide core of MUC2 intestinal mucin. Eur J Cancer 30: 355-63.
11. Filipe MI (1992). Borderline lesions of the gastric epithelium: new indicators of cancer risk and clinical implications. In Progress in Surgical Pathology (eds Fenoglio-Preiser CM, Wolff M, Rilke F); Field and Wood, USA, pp. 269-90.
12. Filipe MI, Lake BD (1990). Appendix 3. In Histochemistry in Pathology. Second Edition (eds Filipe MI, Lake BD); Churchill Livingstone, Edinburgh, pp. 451.
13. Filipe MI, Ramachandra S (1995). The histochemistry of intestinal mucins: changes in disease. In Gastrointestinal and Oesophageal Pathology. Second Edition (ed Whitehead R); Churchill Livingstone, Edinburgh, pp. 73-95.
14. Filipe MI, Munoz N, Kato I et al (1994). Intestinal metaplasia types and the risk of gastric cancer: a cohort study in Slovenia. Int J Cancer 57: 324-9.
15. Guyonnet-Duperat V, Audie JP, Debailleul V et al (1994). Characterization of the human mucin gene MUC5AC: a consensus cysteine-rich domain for 11p15 mucin genes? Biochem J 304: 211-19.
16. Ho SB, Roberton AM, Shekels LL, Lyftogt CT, Niehans GA, Toribara NW (1993). Expression cloning of gastric mucin complementary DNA and localization of mucin gene expression. Gastroenterology 109: 999-1001.
17. Ho SB, Shekels LL, Toribara NW et al (1995). Mucin gene expression in normal, preneoplastic and neoplastic human gastric epithelium. Cancer Res 55: 2681-90.
18. Kennedy BJ (1970). TNM classification for stomach cancer. Cancer 26: 971-83.
19. Laurén P (1965). The two histological main types of gastric carcinoma, diffuse and so called intestinal type carcinoma. An attempt at histoclinical classification. Acta Pathol Microbiol Scand 64: 31-49.
20. Lesuffleur T, Zweibaum A, Real F (1994). Mucins in normal and neoplastic human gastrointestinal tissues. Crit Rev Oncol Hematol 17: 153-80.
21. Lesuffleur T, Roche F, Hill A et al (1995). Characterization of a mucin cDNA clone isolated from HT-29 mucus-secreting cells: the 3′ end of MUC5AC? J Biol Chem 270: 13685-93.
22. Livingstone JE, Filipe MI, Wastell C (1994). Expression of transforming growth factor alpha in experimental gastric carcinogenesis. Gut 35: 604-7.
23. Ming SC (1977). Gastric carcinoma. A pathological classification. Cancer 39: 2475-85.
24. Oota K, Sobin LH (1977). Histological typing of gastric and oesophageal tumours. International Histological Classification of Tumours 18, World Health Organisation, Geneva.
25. Pignatelli B, Malavieille C, Bartsch H (1993). Intragastric mutagens and lowered anti-oxidant defence as risk factors for gastric cancer. Eur J Cancer Prev 2 (Suppl 2): 9-11.
26. Price M, Sekowski M, Ladanyi A et al (1993). Immune recognition of human colonic-tumour-associated MUC2 mucins using an anti-peptide antibody. Int J Cancer 55: 753-9.
27. Rokkas T, Filipe MI, Sladen GE (1991). Detection of an increased incidence of early gastric cancer in patients with intestinal metaplasia type III who are closely followed up. Gut 32: 1110-3.
28. Sprent P (1993). Applied Non-Parametric Statistical Methods. Second Edition. Chapman and Hall, London, p. 145.
29. Toribara N, Roberton A, Ho S et al (1993). Human gastric mucin. Identification of a unique species by expression cloning. J Biol Chem 268: 5879-85.
30. Tytgat K, Buller H, Opdam F, Kim Y, Einerhand A, Dekker J (1994). Biosynthesis of human colonic mucin: MUC2 is the prominent secretory mucin. Gastroenterology 107: 1352-63.
31. Xing PX, Prenzoska J, Layton GT, Devine PL, McKenzie IF (1992). Second generation monoclonal antibodies to intestinal MUC2 peptide reactive with colon cancer. J Natl Cancer Inst 84: 699-703.