Changes in apoptosis after interruption of potent antiretroviral therapy in patients with maximal HIV-1-RNA suppression

AIDS

Volumn 15, Issue 9, 2001, Pages 1178-1181

  Grelli, Sandro ^a   Di Traglia, Loide ^a   Matteucci, Claudia ^a   Lichtner, Miriam ^b   Vullo, Vincenzo ^b   Di Sora, Fiorella ^c   Lauria, Filippo ^c   Montella, Francesco ^c   Favalli, Cartesio ^a   Vella, Stefano ^d   Macchi, Beatrice ^a,e   Mastino, Antonio ^f  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c MOLINETTE HOSPITAL   (Italy)

^d ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^e IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^f UNIVERSITY OF MESSINA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; CD4 ANTIGEN; DIDANOSINE; EFAVIRENZ; LAMIVUDINE; NELFINAVIR; NEVIRAPINE; PROTEINASE INHIBITOR; RITONAVIR; STAVUDINE; VIRUS RNA; ZIDOVUDINE;

APOPTOSIS; ARTICLE; CASE REPORT; CELL DEATH; DISEASE COURSE; DRUG WITHDRAWAL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE COUNT; MALE; PATIENT COMPLIANCE; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; TREATMENT OUTCOME; VIRUS INHIBITION; VIRUS LOAD;

ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; APOPTOSIS; CD4 LYMPHOCYTE COUNT; COHORT STUDIES; FOLLOW-UP STUDIES; HIV INFECTIONS; HIV-1; HUMANS; LONGITUDINAL STUDIES; RNA, VIRAL; VIRAL LOAD;

EID: 0035876157     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-200106150-00014     Document Type: Article

References (12)

1. Antiretroviral therapy in adults: Updated recommendations of the International AIDS Society - USA Panel
2. Immunological effects of antiretroviral therapy
3. Programmed cell death as a mechanism of CD4 and CD8 T cell deletion in AIDS
4. Activation-induced CD4+ T cell death in HIV-positive individuals correlates with Fas susceptibility, CD4+ T cell count, and HIV plasma viral copy number
5. Highly active antiretroviral therapy (HAART) is associated with a lower level of CD4+ T cell apoptosis in HIV-infected patients
6. Spontaneous and anti-Fas induced apoptosis in lymphocytes from HIV-infected patients undergoing highly active anti-retroviral therapy
7. Structured treatment interruptions and treatment intensification
8. Structured treatment interruption in chronically HIV-1 infected patients after long-term viral suppression
9. Changes in CD4 lymphocyte counts after interruption of therapy in patients with failure on protease inhibitor-containing regimens
10. Pre-HAART HIV burden approximates post-HAART viral levels following interruption of therapy in patients with sustained viral suppression
11. Identification of nuclei from apoptotic, necrotic, and viable lymphoid cells by using multiparameter flow cytometry
12. Apoptosis and HIV infection