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Volumn 19, Issue 12, 2001, Pages 2983-2993

Phase I/II trial of the multidrug-resistance modulator valspodar combined with cisplatin and doxorubicin in refractory ovarian cancer

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DOXORUBICIN; GLYCOPROTEIN P; VALSPODAR;

EID: 0035875858     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2001.19.12.2983     Document Type: Article
Times cited : (64)

References (46)
  • 5
    • 0345139075 scopus 로고
    • Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 7785-7789
    • Hamada, H.1    Tsuruo, T.2
  • 9
    • 0031728267 scopus 로고    scopus 로고
    • Multidrug resistance: Clinical relevance in solid tumors strategies for circumvention
    • (1998) Curt Opin Oncol , vol.10 , Issue.SUPPL.
    • Kaye, S.B.1
  • 12
    • 0031436164 scopus 로고    scopus 로고
    • Pharmacologic approaches to reversing multidrug resistance
    • (1997) Semin Hematol , vol.34 , Issue.SUPPL. 5
    • Sikic, B.I.1
  • 13
    • 0026975703 scopus 로고
    • Expression of P-glycoprotein on normal lymphocytes: Enhancement of the doxorubicin sensitivity of concanavalin A-responding mouse spleen cells by P-glycoprotein blockers
    • (1992) Oncol Res , vol.4 , pp. 473-480
    • Pourtier-Manzanedo, A.1    Didier, A.2    Loor, F.3
  • 27
    • 0030666026 scopus 로고    scopus 로고
    • A dose-finding and pharmacokinetic study of reversal of multidrug resistance with SDZ PSC 833 in combination with doxorubicin in patients with solid tumors
    • (1997) Clin Cancer Res , vol.3 , pp. 2005-2015
    • Giaccone, G.1    Linn, S.C.2    Welink, J.3
  • 32
    • 0028560376 scopus 로고
    • Clinical reversal of the multidrug resistance phenotype: True tumour modulation or pharmacokinetic interaction
    • (1994) Eur J Cancer , vol.30 A , pp. 2039-2041
    • Mcleod, H.L.1
  • 34
    • 17644448304 scopus 로고    scopus 로고
    • P-glycoprotein inhibitor valspodar (PSC 833) increases the intracellular concentrations of daunorubicin in vivo in patients with P-glycoprotein-positive acute myeloid leukemia
    • (2000) J Clin Oncol , vol.18 , pp. 1837-1844
    • Tidefelt, U.1    Liliemark, J.2    Gruber, A.3
  • 38
    • 0032742140 scopus 로고    scopus 로고
    • Doxorubicin encapsulated in sterically stabilized liposomes exhibits renal and biliary clearance properties that are independent of valspodar (PSC 833) under conditions that significantly inhibit nonencapsulated drug excretion
    • (1999) Clin Cancer Res , vol.5 , pp. 2939-2947
    • Krishna, R.1    McIntosh, N.2    Riggs, K.W.3
  • 44
    • 0032980591 scopus 로고    scopus 로고
    • Growth inhibition, cytokinesis failure and apoptosis of multidrug-resistant leukemia cells after treatment with P-glycoprotein inhibitory agents
    • (1999) Leukemia , vol.13 , pp. 768-778
    • Lehne, G.1    De Angelis, P.2    Den Boer, M.3
  • 45
    • 0033557521 scopus 로고    scopus 로고
    • SDZ PSC 833, the cyclosporine A analogue and multidrug resistance modulator, activates ceramide synthesis and increases vinblastine sensitivity in drug-sensitive and drug-resistant cancer cells
    • (1999) Cancer Res , vol.59 , pp. 880-885
    • Cabot, M.C.1    Giuliano, A.E.2    Han, T.3
  • 46
    • 0033565728 scopus 로고    scopus 로고
    • Multidrug resistance modulators and doxorubicin synergize to elevate ceramide levels and elicit apoptosis in drug-resistant cancer cells
    • (1999) Cancer , vol.86 , pp. 300-311
    • Lucci, A.1    Han, T.2    Liu, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.