Topically applied clonidine protects the rat retina from ischaemia/reperfusion by stimulating α2-adrenoceptors and not by an action on imidazoline receptors

Brain Research

Volumn 904, Issue 1, 2001, Pages 126-136

  Chao, Hsiao Ming ^a   Osborne, Neville N ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Apraclonidine; Brimonidine; Clonidine; Ischaemia; Neuroprotection; Rat retina

Indexed keywords

AGN 192403; ALPHA 2 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; APRACLONIDINE; BRIMONIDINE; BU 226; CALRETININ; CHOLINE ACETYLTRANSFERASE; CLONIDINE; IMIDAZOLINE RECEPTOR; LIGAND; RAUWOLSCINE; UNCLASSIFIED DRUG; YOHIMBINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ELECTRORETINOGRAM; ENZYME LOCALIZATION; EYE PROTECTION; IMMUNOREACTIVITY; INTRAOCULAR PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; REPERFUSION; RETINA INNER PLEXIFORM LAYER; RETINA ISCHEMIA; SYSTEMIC CIRCULATION; SYSTOLIC BLOOD PRESSURE;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; BICYCLO COMPOUNDS; CALCIUM-BINDING PROTEIN, VITAMIN D-DEPENDENT; CELL DEATH; CHOLINE O-ACETYLTRANSFERASE; CLONIDINE; ELECTRORETINOGRAPHY; HEPTANES; IMMUNOHISTOCHEMISTRY; MEMBRANE POTENTIALS; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; QUINOXALINES; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-2; RECEPTORS, DRUG; REPERFUSION INJURY; RETINA; RETINAL GANGLION CELLS; YOHIMBINE;

EID: 0035875803     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02499-4     Document Type: Article

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