Renal proximal tubule function is preserved in Cftrtm2cam ΔF508 cystic fibrosis mice

Journal of Physiology

Volumn 532, Issue 2, 2001, Pages 449-457

  Kibble, J D ^a   Balloch, K J D ^a   Neal, A M ^a   Hill, C ^a   White, S ^a   Robson, L ^a   Green, R ^a,b   Taylor, C J ^a,c  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c SHEFFIELD CHILDREN S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BUCLADESINE; CHLORIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; DIMETHYL SULFOXIDE; FORSKOLIN; SODIUM; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STIMULATION; CHLORIDE CONDUCTANCE; CONTROLLED STUDY; CYSTIC FIBROSIS; EXTRACELLULAR SPACE; GENOTYPE; KIDNEY CELL; KIDNEY CLEARANCE; KIDNEY CORTEX; KIDNEY FUNCTION; KIDNEY PERFUSION; KIDNEY PRESERVATION; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE ABSORPTION; MOUSE; NATRIURESIS; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ADULT; GENE EXPRESSION; MALE; MOUSE MODEL; RENAL CLEARANCE; SALT LOADING; WHOLE CELL PATCH CLAMP;

ANIMALS; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; KIDNEY TUBULES, PROXIMAL; MALE; MICE; MUTATION; PATCH-CLAMP TECHNIQUES; PERFUSION; PLASMA SUBSTITUTES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SODIUM CHLORIDE;

EID: 0035871121     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.2001.0449f.x     Document Type: Article

References (32)

1. Renal function in patients with cystic fibrosis
2. Renal function with special reference to sodium handling
3. Effects of glucose on water and sodium reabsorption in the proximal convoluted tubule of the rat kidney
4. Plasma concentrations of ADH in conscious and anaesthetized dogs
5. 1A receptor knockout mouse during normal and volume-expanded conditions
6. Generation and characterization of a ΔF508 cystic fibrosis mouse model
7. Immunocytochemical localization of the cystic fibrosis gene product CFTR
8. Diverse modulations of chloride channels in renal proximal tubules
9. Developmental regulation of CFTR expression during human nephrogenesis
10. Impaired diluting segment chloride reabsorption in patients with cystic fibrosis
11. cAMP-regulated whole-cell chloride currents in pancreatic duct cells
12. Improved patch-clamp techniques for high-resolution current recording from cells and cell free membrane patches
13. The ROMK-cystic fibrosis transmembrane conductance regulator connection: New insights into the relationship between ROMK and the cystic fibrosis transmembrane conductance regulator
14. Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance
15. tm2cam mice
16. Pathogenesis of cystic fibrosis
17. Modulation of the ionic permeability of renal cortical brush-border membranes by cAMP
18. - absorption across the thick ascending limb is not altered in cystic fibrosis mice. A role for pseudo-CFTR channel
19. Control of extracellular fluid volume and pathophysiology of edema formation
20. Functional expression and apical localization of the cystic fibrosis transmembrane conductance regulator in MDCK I cells
21. Both the wild-type and a functional isoform of CFTR are expressed in kidney
22. Renal function in patients with cystic fibrosis
23. Chloride currents in primary cultures of rabbit proximal and distal convoluted tubules
24. + channel
25. cAMP-activated chloride channel on the basolateral membrane of renal proximal tubule
26. A chloride channel in the basolateral membrane of rabbit proximal tubule
27. - conductance by cAMP in rabbit renal proximal tubule S3 segments
28. Cystic fibrosis transmembrane conductance regulator (CFTR) and renal function
29. Decreased renal clearance of sodium in cystic fibrosis
30. - channel activated by parathyroid hormone in rabbit renal proximal tubule cells
31. Stimulation of chloride transport by cAMP in rat proximal tubules
32. Mechanism of proximal tubule bicarbonate absorption in NHE3 null mice