Spider neurotoxins block the β scorpion toxin-induced calcium uptake in rat brain cortical synaptosomes

Brain Research Bulletin

Volumn 54, Issue 5, 2001, Pages 533-536

  Miranda, D M ^a   Romano Silva, M A ^a   Kalapothakis, E ^a   Diniz, C R ^b   Cordeiro, M N ^b   Moraes Santos, T ^a   De Marco, L ^a   Prado, M A M ^a   Gomez, M V ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b FUNDAÇÃO EZEQUIEL DIAS   (Brazil)

Author keywords

Calcium channels; Calcium uptake; Spider toxins; Synaptosomes; Tityus toxin

Indexed keywords

CALCIUM 45; CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; NEUROTOXIN; OMEGA AGATOXIN IVA; OMEGA CONOTOXIN MVIIC; SCORPION TOXIN TITYUS GAMMA; SCORPION VENOM; SPIDER TOXIN TX3-3; SPIDER TOXIN TX3-4; SPIDER VENOM; UNCLASSIFIED DRUG; VERAPAMIL;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG INTERACTION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTOSOME;

ANIMALS; BRAIN; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CEREBRAL CORTEX; DRUG INTERACTIONS; NEURONS; NEUROPEPTIDES; NEUROTOXINS; RATS; RATS, WISTAR; SCORPION VENOMS; SPIDER VENOMS; SYNAPTOSOMES;

EID: 0035867029     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(01)00443-9     Document Type: Article

References (27)

1. Gapped BLAST and PSI BLAST; A new generation of protein database search programs
2. + channel
3. 3H]acetylcholine from rat brain cortical slices
4. ω-Phonetoxin-IIA; A calcium channel blocker from the spider Phoneutria nigriventer
5. Purification and amino acid sequences of six TX3 type neurotoxins from the venom of the Brazilian 'armed' spider Phoneutria nigriventer
6. A rapid percoll gradient procedure for isolation of synaptosomes directly from S1 fraction; Homogeneity and morphology of subcellular fraction
7. Separation of toxic components from the Brazilian scorpion Tityus serrulatus venom
8. 3H-acetylcholine induced by tityustoxin and potassium in brain cortical slices and myenteric plexus
9. ω-Conotoxin MVIIC irreversibly inhibits a human N-type calcium channel and calcium influx into chicken synaptosomes
10. A toxin from the spider Phoneutria nigriventer that blocks calcium channels coupled to exocytosis
11. Protein measurements with the Folin phenol reagent
12. 2+ channels
13. 2+ ions in their function and desentization
14. i
15. Tityustoxin and toxin gamma; Comparative study of their effects on acetylcholine release from rat brain cortical slices
16. 2+ channels present in synaptosomes from rat and chicken central nervous system
17. Inhibition of calcium channels in rat central and peripheral neurons by ω-Conotoxin MVIIC
18. Multiples calcium channels and neuronal function
19. Phoneutria nigriventer toxins block tityustoxin-induced calcium influx in synaptosomes
20. Calcium channel diversity and neurotransmitter release; The ω-conotoxin and ω-Agatoxins
21. A novel tool for the investigation of glutamate release from rat cerebrocortical synaptosomes; the toxin from Tx3-3 from the venom of the spider Phoneutria nigriventer
22. Pharmacological dissection of multiple types of calcium channel currents in rat cerebellar neurons
23. Isolation of neurotoxic peptides from the venom of the 'armed spider' Phoneutria nigriventer
24. 2+-dependent glutamate release from synaptosomes
25. Isolation and characterization of toxic proteins from the venom of the Brazilian scorpion Tityus serrulatus
26. Further characterization of phasic calcium influx in rat cerebro cortical synaptosomes; Interferences regarding calcium channel type(s) in nerve ending
27. + channels in neuroblastome