Novel glucocorticoid antedrugs possessing a 17β-(γ-lactone) ring

Journal of Medicinal Chemistry

Volumn 44, Issue 4, 2001, Pages 602-612

  Procopiou, P A ^a   Biggadike, K ^a   English, A F ^a   Farrell, R M ^a   Hagger, G N ^a   Hancock, A P ^a   Haase, M V ^a   Irving, W R ^a   Sareen, M ^a   Snowden, M A ^a   Solanke, Y E ^a   Tralau Stewart, C J ^a   Walton, S E ^a   Wood, J A ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARYLDIALKYLPHOSPHATASE; BUDESONIDE; DEXAMETHASONE; FLUOCINOLONE ACETONIDE; FLUTICASONE PROPIONATE; GAMMA BUTYROLACTONE DERIVATIVE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HYDROXYACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DECARBOXYLATION; DRUG HYDROLYSIS; DRUG RECEPTOR BINDING; DRUG STABILITY; DRUG STRUCTURE; EDEMA; HUMAN; HUMAN CELL; INVOLUTION; MALE; NONHUMAN; PLASMA; RAT; STRUCTURE ACTIVITY RELATION; THYMUS;

ADMINISTRATION, TOPICAL; ANIMALS; ANTI-INFLAMMATORY AGENTS; BUTYRIC ACIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; EDEMA; GLUCOCORTICOIDS; HELA CELLS; HUMANS; LACTONES; LUNG; MALE; ORGAN SIZE; RATS; RECEPTORS, GLUCOCORTICOID; STRUCTURE-ACTIVITY RELATIONSHIP; THYMUS GLAND;

EID: 0035865829     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm001035c     Document Type: Article

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