Indirectly primed CD8+ T cells are a prominent component of the allogeneic T-cell repertoire after skin graft rejection in mice

Transplantation

Volumn 71, Issue 3, 2001, Pages 418-421

  Valujskikh, Anna ^a   Hartig, Carsten ^a   Heeger, Peter S ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; GAMMA INTERFERON;

ALLOGRAFT; ALLOIMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GRAFT REJECTION; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SKIN GRAFT; T LYMPHOCYTE;

EID: 0035865240     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200102150-00014     Document Type: Article

References (17)

1. Donor major histocompatibility complex (MHC) peptides are presented by recipient MHC molecules during graft rejection
2. The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice
3. Contribution of direct and indirect recognition pathways to T cell alloreactivity
4. Contributions of direct and indirect T cell alloreactivity during allograft rejection in mice
5. Antigen processing and presentation in transplantation
6. Effector cells must recognize antigens expressed in the graft to cause efficient skin graft rejection in SCID mice
7. T cells reactive to a single immunodominant self-restricted allopeptide induce skin graft rejection in mice
8. Antigen processing and presentation by the class I major histocompatibility complex
9. Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not crossreact in the cytotoxic assay
10. Direct evidence for in vivo induction of CD8+ cytotoxic T cells directed to donor MHC class I peptides following mouse allotransplantation
11. High-resolution characterization of cytokine-producing alloreactivity in naive and allograft-primed mice
12. Type 2 immune deviation has differential effects on alloreactive CD4+ and CD8+ T cells
13. In vivo depletion of CD8+ T cells results in Th2 cytokine production and alternate mechanisms of allograft rejection
14. In vivo cross-priming of MHC class I-restricted antigens requires the TAP transporter
15. A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides
16. CD8+ T cell-dependent elimination of dendritic cells in vivo limits the induction of antitumor immunity
17. Limited T cell response to donor MHC peptides during allograft rejection: Implications for selective immune therapy in transplantation