Role of the CD95/CD95 ligand system in glucocorticoid-induced monocyte apoptosis

Journal of Immunology

Volumn 166, Issue 2, 2001, Pages 1344-1351

  Schmidt, M ^a   Lugering N ^a   Lugering A ^a   Pauels, H G ^a   Schulze Osthoff, K ^a   Domschke, W ^a   Kucharzik, T ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; FAS ANTIGEN; GLUCOCORTICOID; IMMUNOSUPPRESSIVE AGENT; LIPOCORTIN 5; MIFEPRISTONE;

APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; LIGAND BINDING; MEDIATOR RELEASE; MEMBRANE BINDING; MONOCYTE; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR UPREGULATION;

EID: 0035863757     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.2.1344     Document Type: Article

References (51)

1. Glucocorticoids inhibit the production of IL-6 from monocytes, endothelial cells and fibroblasts
2. Analysis of the suppression of IL-1α and IL-1β production in human peripheral blood mononuclear adherent cells by a glucocorticoid hormone
3. Glucocorticoid modulation of human monocyte/macrophage function: Control of TNF-α secretion
4. Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor
5. Domains of the glucocomcoid receptor revolved in specific and nonspecific deoxyribonucleic acid binding, hormone activation, and transcriptional enhancement
6. The glucocorticoid receptor
7. Regulation of interleukin-1β production by glucocorticoids in human monocytes: The mechanism of action depends on the activation signal
8. Hydrocortisone regulation of interleukiun-6 protein production by a purified population of human peripheral blood monocytes
9. Signal transduction pathways leading to the production of IL-8 by human monocytes are differentially regulated by dexamethasone
10. Glucocorticoids induce apoptosis in human monocytes: Potential role of interleukin-1β
11. The effect of glucocorticosteroids on the kinetics of mononuclear phagocytes
12. Influence of topically and systemically active steroids on circulating leukocytes in Crohn's disease
13. Differential induction of apoptosis by Fas-Fas ligand interactions in human monocytes and macrophages
14. Lipopolysaccharide, tumor necrosis factor-α, and IL-1β prevent programmed cell death (apoptosis) in human peripheral blood monocytes
15. Differential regulation of human monocyte programmed cell death (apoptosis) by chemotactic factors and pro-inflammatory cytokines
16. Human monocytic cells contain high levels of intracellular Fas ligand: Rapid release following cellular activation
17. Phagocytosis triggers macrophage release of Fas ligand and induces apoptosis of bystander leukocytes
18. Apoptosis signaling by death receptors
19. Apoptosis by death factor
20. Cytotoxicity-dependent APO-1 (Fas/ CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
21. FLICE, a novel FADDhomologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
22. The role of caspases in development, immunity, and apoptotic signal transduction: Lessons from knockout mice
23. Anticancer drugs induce caspase-8 activation and apoptosis in the absence of CD95 receptor/ligand interaction
24. + T cell apoptosis: A possible mechanism of bystander cell death in HIV infection
25. Constitutive expression of Fas (APO-1/CD95) ligand on multiple myeloma cells: A potential mechanism of tumor-induced suppression of immune surveillance
26. Regulation of human monocytes apoptosis by the CD14 molecule
27. Glucocorticoids promote nonphlogistic phagocytosis of apoptotic leukocytes
28. Yama/CPPβ32, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
29. CPP32/apopain is a key interleukin 1β converting enzyme-like protease involved in Fas-mediated apoptosis
30. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
31. The polypoptide encoded by the eDNA for human cell surface antigen Fas can mediate apoptosis
32. Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen
33. Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule
34. Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids
35. Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis
36. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
37. Spontaneous and glucocorticoid-induced apoptosis in human mature T lymphocytes
38. Glucocorticoids activate a suicide program in mature T lymphocytes: Protective action of interleukin 2
39. Fas and Fas ligand expression on human peripheral blood leukocytes
40. Quantification of Bax/Bcl-2 ratios in peripheral blood lymphocytes, monocytes and granulocytes and their relation to susceptibility to anti-Fas (anti-CD95)-induced apoptosis
41. Membrane and soluble forms of Fas (CD95) and Fas ligand in peripheral blood mononuclear cells and in plasma from human immanodeficiency virus-infected persons
42. Monocytes express Fas ligand upon CD4 cross-linking and induce CD4 T cells apoptosis
43. An overview of glucocorticoid anti-inflammatory actions
44. Glucocorticosteroid therapy: Mechanisms of action and clinical considerations
45. Spontaneous human monocyte apoptosis utilizes a caspase-3-dependent pathway that is blocked by endotoxin and is independent of caspase-1
46. Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
47. Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: Inhibition of Fas ligand expression by retinoic acid and glucocorticoids
48. Regulation of CD95 (APO-1/Fas) receptor and ligand expression by lipopolysaccharide and dexamethasone in parenchymal and nonparenchymal rat liver cells
49. Constitutive Fas ligand gene transcription in Sertoli cells is regulated by Spl
50. An essential role for NFκB in preventing TNFα-induced cell death
51. Activate NF-κB or die?