HIV-1 Preintegration Complexes Preferentially Integrate into Longer Target DNA Molecules in Solution as Detected by a Sensitive, Polymerase Chain Reaction-based Integration Assay

Journal of Biological Chemistry

Volumn 276, Issue 50, 2001, Pages 46946-46952

  Brooun, Alexei ^a,d   Richman, Douglas D ^a,b,c   Kornbluth, Richard S ^a,e  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^d Takeda San Diego Inc   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CELLS; DNA; DNA SEQUENCES; FLUORESCENCE; GENES; MOLECULES; SOLUTIONS;

REVERSE TRANSCRIPTION;

VIRUSES;

DNA; INTEGRASE INHIBITOR; L EXONUCLEASE; PREINTEGRATION COMPLEX INHIBITOR; UNCLASSIFIED DRUG; VIRUS DNA; COMPLEMENTARY DNA; INORGANIC SALT; PRIMER DNA;

ANIMAL CELL; ARTICLE; BASE PAIRING; COMPLEX FORMATION; DNA SEQUENCE; ENZYME DEGRADATION; FLUORESCENCE; GENE TARGETING; HOST CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LONG TERMINAL REPEAT; NONHUMAN; POLYMERASE CHAIN REACTION; PREINTEGRATION COMPLEX; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; REAL TIME FLUORESCENCE MONITORING POLYMERASE CHAIN REACTION AMPLIFICATION; RETROVIRUS; REVERSE TRANSCRIPTION; VIRUS GENOME; BINDING COMPETITION; BIOLOGICAL MODEL; CYTOPLASM; DOSE RESPONSE; ENZYME SPECIFICITY; GENETICS; METABOLISM; METHODOLOGY; PLASMID; PROTEIN BINDING; TIME;

ANIMALIA; DNA VIRUSES; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES; UNIDENTIFIED RETROVIRUS;

BINDING, COMPETITIVE; CYTOPLASM; DNA; DNA PRIMERS; DNA, COMPLEMENTARY; DNA, VIRAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HIV-1; MODELS, GENETIC; PLASMIDS; POLYMERASE CHAIN REACTION; PROTEIN BINDING; SALTS; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS;

EID: 0035861651     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M108000200     Document Type: Article

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