Definition of the Extended Substrate Specificity Determinants for β-Tryptases I and II

Journal of Biological Chemistry

Volumn 276, Issue 37, 2001, Pages 34941-34947

  Harris, Jennifer L ^a,d   Niles, Andrew ^b   Burdick, Keith ^a   Maffitt, Mark ^b   Backes, Bradley J ^c,d   Ellman, Jonathan A ^c   Kuntz, Irwin ^a   Haak Frendscho, Mary ^b   Craik, Charles S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b PROMEGA CORPORATION   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; DATA REDUCTION; ENZYMES; SCANNING;

SUBSTRATE BINDING;

BIOCHEMISTRY;

ARGININE; ASPARAGINE; LYSINE; PROLINE; TRYPTASE; TRYPTASE BETAI; TRYPTASE BETAII; UNCLASSIFIED DRUG; ISOENZYME; RECOMBINANT PROTEIN; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR;

ARTICLE; ENZYME RELEASE; ENZYME SPECIFICITY; ENZYME STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRUCTURE ANALYSIS; CHEMISTRY; GENETICS; HUMAN; METABOLISM; PICHIA;

HUMANS; ISOENZYMES; PICHIA; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; SUBSTRATE SPECIFICITY; TRYPTASES;

EID: 0035860703     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M102997200     Document Type: Article

References (26)

1. Schwartz, L., Lewis, R., and Austen, K. (1981) J. Biol. Chem. 256, 11939-11943
2. Pereira, P. J. B., Bergner, A., Macedo-Ribeiro, S., Huber, R., Matschiner, C., Fritz, H., Sommerhoff, C. P., and Bode, W. (1998) Nature 392, 306-311
3. Molino, M., Barnathan, E., Numerof, R., Clark, J., Drever, M., Cumashi, A., Hoxie, J., Schechter, N., Woolkalis, M., and Brass, L. (1997) J. Biol. Chem. 272, 4043-4049
4. Stack, M., and Johnson, D. (1994) J. Biol. Chem. 269, 9416-9419
5. Tam, E., and Caughey, G. (1990) Am. J. Respir. Cell Mol. Biol. 3, 27-32
6. Coussens, L. M., Raymond, W. W., Bergers, G., Laig-Webster, M., Behrendtsen, O., Werb, Z., Caughey, G. H., and Hanahan, D. (1999) Genes Dev. 13, 1382-1397
7. Pallaoro, M., Fejzo, M., Shayesteh, L., Blount, J., and Caughey, G. (1999) J. Biol. Chem. 274, 3355-3362
8. Caughey, G. H., Raymond, W. W., Blount, J. L., Hau, L. W.-T., Pallaoro, M., Wolters, P. J., and Verghese, G. M. (2000) J. Immunol. 164, 6566-6575
9. Huang, C., Li, L., Krilis, S., Chanasyk, K., Tang, Y., Li, Z., Hunt, J., and Stevens, R. (1999) J. Biol. Chem. 274, 19670-19676
10. Harris, J., Backes, B., Leonetti, F., Mahrus, S., Ellman, J., and Craik, C. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 7754-7759
11. Niles, A. L., Maffitt, M., Haak-Frendscho, M., Wheeless, C. J., and Johnson, D. A. (1998) Biotechnol. Appl. Biochem. 28, 125-131
12. Jameson, G., Roberts, D. V., Adams, R. W., Kyle, W. S., and Elmore, D. T. (1973) Biochem. J. 131, 107-117
13. Backes, B. J., Harris, J. L., Leonetti, F., Craik, C. S., and Ellman, J. A. (2000) Nat. Biotechnol. 18, 187-193
14. Bieth, J. G. (1995) Methods Enzymol. 248, 59-84
15. Rice, K., Tanaka, R., Katz, B., Numerof, R., and Moore, W. (1998) Curr. Pharm. Des. 4, 381-396
16. Cornell, W. D., Cieplak, P., Bayly, C. I., Gould, I. R., Merz, K. M., Ferguson, D. M., Spellmeyer, D. C., Fox, T., Caldwell, J. W., and Kollman, P. A. (1995) J. Am. Chem. Soc. 117, 5179-5197
17. Ewing, T. J. A., Makino, S., Skillman, A. G., and Kuntz, I. D. (2001) J. Comput. Aided Mol. Des. 15, 411-428
18. Weiner, S. J., Kollman, P. A., Nguyen, D. T., and Case, D. A. (1986) J. Comput. Chem. 7, 230-252
19. Lamb, M. L., Burdick, K. W., Toba, S., Arnold, J. R., Skillman, A. G., Young, M., Zou, X., and Kuntz, I. D. (2001) Proteins 42, 296-318
20. Harris, J. L., Peterson, E. P., Hudig, D., Thornberry, N. A., and Craik, C. S. (1998) J. Biol. Chem. 273, 27364-27373
21. Tanaka, T., McRae, B. J., Cho, K., Cook, R., Fraki, J. E., Johnson, D. A., and Powers, J. C. (1983) J. Biol. Chem. 258, 13552-13557
22. Meng, E. C., Shoichet, B. K., and Kuntz, I. D. (1992) J. Comput. Chem. 13, 505-524
23. Takanami, I., Takeuchi, K., and Naruke, M. (2000) Cancer 88, 2686-2692
24. Toth-Jakatics, R., Jimi, S., Takebayashi, S., and Kawamoto, N. (2000) Hum. Pathol. 31, 955-960
25. Ribatti, D., Vacca, A., Marzullo, A., Nico, B., Ria, R., Roncali, L., and Dammacco, F. (2000) Int. J. Cancer 85, 171-175
26. Burgess, L., Newhouse, B., Ibrahim, P., Rizzi, J., Kashem, M., Hartman, A., Brandhuber, B., Wright, C., Thomson, D., Vigers, G., and Koch, K. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 8348-8352