Detection of DNA damage induced by human carcinogens in acellular assays: Potential application for determining genotoxic mechanisms

Mutation Research - Genetic Toxicology

Volumn 368, Issue 3-4, 1996, Pages 235-248

  Adams, Stephen P ^a   Laws, George M ^a   Storer, Richard D ^a   DeLuca, John G ^a   Nichols, Warren W ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

8 Hydroxydeoxyguanosine; 32P Postlabeling; Alkaline gel electrophoresis; DNA adducts; DNA fragmentation; Electrochemical detection; Laser densitometry; Multifraction contact transfer thin layer chromatography

Indexed keywords

2 NAPHTHYLAMINE; AFLATOXIN B1; BUSULFAN; CARCINOGEN; CHLORAMBUCIL; CYCLOPHOSPHAMIDE; DIETHYLSTILBESTROL; MELPHALAN; PHENACETIN; POTASSIUM CHROMATE;

ARTICLE; BACTERIOPHAGE LAMBDA; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; ELECTROCHEMICAL DETECTION; GEL ELECTROPHORESIS; GENETIC TOXICOLOGY; GENOTOXICITY; IN VITRO STUDY; ISOTOPE LABELING; METABOLIC ACTIVATION; NONHUMAN; PRIORITY JOURNAL; TECHNIQUE; THIN LAYER CHROMATOGRAPHY;

EID: 0030570549     PISSN: 01651218     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1218(96)90065-8     Document Type: Article

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