Propofol activates vanilloid receptor channels expressed in human embryonic kidney 293 cells

Neuroscience Letters

Volumn 312, Issue 1, 2001, Pages 45-49

  Tsutsumi, Satoshi ^a   Tomioka, Akihiro ^a   Sudo, Makoto ^a   Nakamura, Akio ^a   Shirakura, Kenji ^a   Takagishi, Kenji ^a   Kohama, Kazuhiro ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

Calcium imaging; Capsaicin; Human embryonic kidney 293 cell; Intravenous anesthetic; Propofol; Vanilloid receptor

Indexed keywords

ANESTHETIC AGENT; CALCIUM; CALCIUM ION; CAPSAICIN; CAPSAZEPINE; CELL RECEPTOR; PROPOFOL; VANILLOID RECEPTOR;

ANESTHESIA; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVATION; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; EMBRYO; EXTRACELLULAR CALCIUM; HUMAN; HUMAN CELL; IMAGING; KIDNEY CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANESTHETICS, INTRAVENOUS; BINDING SITES; CALCIUM; CALCIUM SIGNALING; CAPSAICIN; CELLS, CULTURED; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MEMBRANE POTENTIALS; NERVOUS SYSTEM; PAIN; PATCH-CLAMP TECHNIQUES; PROPOFOL; RECEPTORS, DRUG;

EID: 0035850979     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(01)02185-1     Document Type: Article

References (18)

1. Capsazepine: A competitive antagonist of the sensory neurone excitant capsaicin
2. The capsaicin receptor: A heat-activated ion channel in the pain pathway
3. Unilateral convulsion after induction of anaesthesia with propofol
4. Human brain sodium channels as one of the molecular target sites for the new intravenous anaesthetic propofol (2,6-diisopropylphenol)
5. Molecular and cellular mechanisms of general anaesthesia
6. Disposition of propofol administered as constant rate intravenous infusions in humans
7. The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones
8. Capsaicin-sensitive nerves in the control of vascular effector mechanisms
9. Characterization using FLIPR of rat vanilloid receptor (rVR1) pharmacology
10. Inhibition by propofol (2,6 di-isopropylphenol) of the N-methyl-D-aspartate subtype of glutamate receptor in cultured hippocampal neurones
11. Propofol and seizures
12. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase
13. The cloned capsaicin receptor integrates multiple pain-producing stimuli
14. 4 receptor channels expressed in human embryonic kidney 293 cells
15. Mechanisms of propofol action on ion currents in the myelinated axon of Xenopus laevis
16. Cellular mechanism of action of resiniferatoxin: A potent sensory neuron excitotoxin
17. Effects of propofol on various AMPA-, kainate- and NMDA-selective glutamate receptor channels expressed in Xenopus oocytes
18. Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide