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Volumn 297, Issue 2, 2001, Pages 113-116

The small molecule FKBP ligand GPI 1046 induces partial striatal re-innervation after intranigral 6-hydroxydopamine lesion in rats

(6) Ross, Douglas T a Guo, Hongzhi a Howorth, Pamela a Chen, Yi a Hamilton, Gregory S a Steiner, Joseph P a

a GUILFORD PHARMACEUTICALS INC (United States)

Author keywords

FK 506; FKBP; Parkinson's disease; Re innervation; Sprouting

Indexed keywords

1 (3,3 DIMETHYL 1,2 DIOXOPENTYL) 2 PYRROLIDINECARBOXYLIC ACID 3 (3 PYRIDYL)PROPYL ESTER; DRUG BINDING PROTEIN; OXIDOPAMINE; TACROLIMUS; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAUDATE NUCLEUS; CONTROLLED STUDY; CORPUS STRIATUM; DEAFFERENTATION; DRUG EFFECT; IMMUNOHISTOCHEMISTRY; MALE; NERVE REGENERATION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PUTAMEN; RAT; REINNERVATION; SUBSTANTIA NIGRA;

ANIMALS; CORPUS STRIATUM; LIGANDS; MALE; NERVE DEGENERATION; NERVE FIBERS; NERVE REGENERATION; OXIDOPAMINE; PARKINSON DISEASE; PYRROLIDINES; RATS; RATS, SPRAGUE-DAWLEY; SYMPATHOLYTICS; TACROLIMUS BINDING PROTEINS; TYROSINE 3-MONOOXYGENASE;

EID: 0035846834 PISSN: 03043940 EISSN: None Source Type: Journal
DOI: 10.1016/S0304-3940(00)01683-9 Document Type: Article

Times cited : (33)

References (20)

1
- 0033104019
- Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor
- (1999) J. Neurosci. , vol.19 , pp. 1708-1716
- Batchelor, P.E.¹ Liberatore, G.T.² Wong, J.Y.³ Porritt, M.J.⁴ Frerichs, F.⁵ Donnan, G.A.⁶ Howells, D.W.⁷

2
- 0023225802
- Adrenal medulla grafts enhance recovery of striatal dopaminergic fibers
- (1987) Science , vol.237 , pp. 913-916
- Bohn, M.C.¹ Cupit, L.² Marciano, F.³ Gash, D.M.⁴

3
- 0029764836
- 6-Hydroxydopamine induces the loss of the dopaminergic phenotype in substantia nigra neurons of the rat. A possible mechanism for restoration of the nigrostriatal circuit mediated by glial cell line-derived neurotrophic factor
- (1996) Exp. Brain Res. , vol.111 , pp. 1-7
- Bowenkamp, K.E.¹ David, D.² Lapchak, P.L.³ Henry, M.A.⁴ Granholm, A.C.⁵ Hoffer, B.J.⁶ Mahalik, T.J.⁷

4
- 0000045218
- Neuroprotective and regenerative effects of immunophilin ligands in an animal model of Parkinson's disease
- (1997) Soc. Neurosci. Abstr. , vol.23 , pp. 1452
- Constantini, L.C.¹ Chaturvedi, P.² McCaffrey, P.³ Deacon, T.W.⁴ Isacson, O.⁵

5
- 0032542346
- Immunophilins: Beyond immunosuppression
- (1998) J. Med. Chem. , vol.41 , pp. 5119-5143
- Hamilton, G.S.¹ Steiner, J.P.²

6
- 0030799884
- Neuroimmunophilin ligands as novel therapeutics for the treatment of degenerative disorders of the nervous system
- (1997) Curr. Pharm. Design , vol.3 , pp. 405-428
- Hamilton, G.S.¹ Steiner, J.P.²

7
- 0021159379
- Cyclophilin: A specific cytosolic binding protein for cyclosporin A
- (1984) Science , vol.226 , pp. 544-547
- Handschumacher, R.E.¹ Harding, M.W.² Rice, J.³ Drugge, R.J.⁴ Speicher, D.W.⁵

8
- 0032889368
- Analysis of the neurotrophic effects of GPI 1046 on neuron survival and regeneration in culture and in vivo
- (1999) Neuroscience , vol.88 , pp. 257-267
- Harper, S.¹ Bilsland, J.² Young, L.³ Bristow, L.⁴ Boyce, S.⁵ Mason, G.⁶ Rigby, M.⁷ Hewson, L.⁸ Smith, D.⁹ O'Donnell, R.¹⁰ O'Connor, D.¹¹ Hill, R.G.¹² Evans, D.¹³ Swain, C.¹⁴ Williams, B.¹⁵ Hefti, F.¹⁶

9
- 0030200666
- Dopaminergic responses to striatal damage
- (1996) J. Neurol. Sci. , vol.139 , pp. 125-130
- Howells, D.W.¹ Liberatore, G.T.² Wong, J.Y.³ Donnan, G.A.⁴

10
- 0028874203
- GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo
- (1995) Brain Res. , vol.672 , pp. 104-111
- Kearns, C.M.¹ Gash, D.M.²

11
- 0002561043
- Increased dopaminergic activity caused by striatal injury is associated with axonal sprouting
- (1996) Soc. Neurosci. Abstr. , vol.22 , pp. 1493
- Liberatore, G.¹ Finklestein, D.² Wong, J.³ Horne, M.⁴ Donnan, G.⁵ Howells, D.W.⁶

12
- 0026076047
- The neuropathologic basis of different clinical subgroups of Parkinson's disease
- (1991) J. Neuropathol. Exp. Neurol. , vol.50 , pp. 743-755
- Paulus, W.¹ Jellinger, K.²

13
- 0344265121
- Novel neuroimmunophilin ligands for FKBP-12 possess potent neurotrophic activity in the mouse MPTP model of Parkinson's disease
- (1996) Soc. Neurosci. Abstr. , vol.22 , pp. 738
- Ross, D.T.¹ Valentine, H.L.² Guo, H.³ Hamilton, G.S.⁴ Huang, W.⁵ Suzdak, P.D.⁶ Steiner, J.P.⁷

14
- 0026030568
- Chemistry and biology of the immunophilins and their immunosuppressive ligands
- (1991) Science , vol.251 , pp. 283-287
- Schreiber, S.L.¹

15
- 0029035602
- BDNF attenuates the effects of intrastriatal injection of 6-hydroxydopamine
- (1995) NeuroReport , vol.6 , pp. 1109-1112
- Shults, C.W.¹ Kimber, T.² Altar, C.A.³

16
- 0002461162
- The orally active neuroimmunophilin ligand GPI 1046 stimulates functional recovery in a mouse model of Parkinson's disease
- submitted for publication
- (2000) J. Pharm. Exp. Ther.
- Steiner, J.¹ Ross, D.² Sauer, H.³ Hamilton, G.⁴ Valentine, H.⁵ Guo, H.⁶ Liang, S.⁷ Spicer, D.⁸ Howorth, P.⁹ Chen, Y.¹⁰ Fuller, M.¹¹ Suzdak, P.¹²

17
- 0030975605
- Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A
- (1997) Nat. Med. , vol.3 , pp. 421-428
- Steiner, J.P.¹ Connolly, M.A.² Valentine, H.L.³ Hamilton, G.S.⁴ Dawson, T.M.⁵ Hester, L.⁶ Snyder, S.H.⁷

18
- 0026673772
- High brain densities of the immunophilin FKBP colocalized with calcineurin
- (1992) Nature , vol.358 , pp. 584-587
- Steiner, J.P.¹ Dawson, T.M.² Fotuhi, M.³ Glatt, C.E.⁴ Snowman, A.M.⁵ Cohen, N.⁶ Snyder, S.H.⁷

19
- 12644257556
- Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models
- (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 2019-2024
- Steiner, J.P.¹ Hamilton, G.S.² Ross, D.T.³ Valentine, H.L.⁴ Guo, H.⁵ Connolly, M.A.⁶ Liang, S.⁷ Ramsey, C.⁸ Li, J.H.⁹ Huang, W.¹⁰ Howorth, P.¹¹ Soni, R.¹² Fuller, M.¹³ Sauer, H.¹⁴ Nowotnik, A.C.¹⁵ Suzdak, P.D.¹⁶

20
- 0028181878
- A 6-hydroxydopamine-induced selective parkinsonian rat model: Further biochemical and behavioral characterization
- (1994) Exp. Neurol. , vol.126 , pp. 159-167
- Thomas, J.¹ Wang, J.² Takubo, H.³ Sheng, J.⁴ De Jesus, S.⁵ Bankiewicz, K.S.⁶

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