Emulsions containing partially water-miscible solvents for the preparation of drug nanosuspensions

Journal of Controlled Release

Volumn 76, Issue 1-2, 2001, Pages 119-128

  Trotta, Michele ^a   Gallarate, Marina ^a   Pattarino, Franco ^a   Morel, Silvia ^a  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

Dissolution; Emulsion; Nanoparticles; Solvent quenching

Indexed keywords

BENZYL ALCOHOL; BUTYL LACTATE; CAPRYLYLCAPRYL GLUCOSIDE; EMULSIFYING AGENT; LACTIC ACID DERIVATIVE; MITOTANE; NANOPARTICLE; PHOSPHATIDYLCHOLINE; POLYSORBATE 80; TRIACETIN; UNCLASSIFIED DRUG; WATER;

AQUEOUS SOLUTION; ARTICLE; DRUG BIOAVAILABILITY; DRUG DIFFUSION; DRUG DOSAGE FORM; DRUG PURIFICATION; DRUG SOLUBILITY; DRUG SYNTHESIS; EMULSION; MISCIBILITY; PARTICLE SIZE; PRIORITY JOURNAL; SUSPENSION;

EMULSIONS; PARTICLE SIZE; SOLUBILITY; SUSPENSIONS;

EID: 0035845740     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00432-1     Document Type: Article

References (18)

1. Nanosuspensions of poorly soluble drugs - Reproducibility of small scale production
2. Supercritical fluids: An interesting medium for chemical and biochemical processes
3. Solvent selection in the preparation of poly(DL-lactide) microspheres prepared by the solvent evaporation method
4. Microencapsulation technique using ethyl acetate as a dispersed solvent: Effects of its extraction rate on the characteristics of PLGA microspheres
5. Ethyl formate-alternative dispersed solvent useful in preparing PLGA microspheres
6. Process of formation of nanoparticles by the emulsification-diffusion technique based on the diffusion-stranding mechanism
7. Carcinoma of the adrenal cortex
8. Submicron emulsions as colloidal drug carriers for intravenous administration: Comprehensive physicochemical characterisation
9. Combined use of lecithin and decyl polyglucoside in microemulsions: Domain of existence and cosurfactant effect
10. Investigation of the phase behaviour of systems containing lecithin and 2-acyl lysolecithin derivatives
11. Descriptions of interaction process in agitated liquid-liquid dispersions
12. Analysis of droplet coalescence in turbulent liquid-liquid dispersions
13. Study of the formation mechanism of nanoparticles by the emulsion-diffusion technique
14. Characteristics and significance of the amorphous state in pharmaceutical system