Subdomain-specific localization of CLIMP-63 (p63) in the endoplasmic reticulum is mediated by its luminal α-helical segment

Journal of Cell Biology

Volumn 153, Issue 6, 2001, Pages 1287-1299

  Klopfenstein, Dieter R ^a   Klumperman, Judith ^b   Lustig, Ariel ^a   Kammerer, Richard A ^a   Oorschot, Viola ^b   Hauri, Hans Peter ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

CLIMP 63 (p63); Coiled coils; Endoplasmic reticulum; Green fluorescent protein; Microtubule binding membrane protein

Indexed keywords

GREEN FLUORESCENT PROTEIN; PROTEIN P63; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CELL STRAIN COS1; CELLULAR DISTRIBUTION; CIRCULAR DICHROISM; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; IMMUNOGOLD ELECTRON MICROSCOPY; MICROTUBULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BINDING SITES; CERCOPITHECUS AETHIOPS; COS CELLS; ENDOPLASMIC RETICULUM; MEMBRANE PROTEINS; NUCLEAR ENVELOPE; PHOSPHOPROTEINS; RECOMBINANT FUSION PROTEINS; TRANS-ACTIVATORS;

ANIMALIA;

EID: 0035844877     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.153.6.1287     Document Type: Article

References (54)

1. The pathway of assembly of intermediate filaments from recombinant alpha-internexin
2. Transport pathways of macromolecules between the nucleus and the cytoplasm
3. Mapping the interaction between GRASP65 and GM130, components of a protein complex involved in the stacking of Golgi cisternae
4. Nuclear pore complex proteins
5. Association of spectrin with a subcompartment of the endoplasmic reticulum in honeybee photoreceptor cells
6. Intracellular signaling from the endoplasmic reticulum to the nucleus
7. Determination of the helix and beta-form of proteins in aqueous solution by circular dichroism
8. Diffusional mobility of Golgi proteins in membranes of living cells
9. Signaling and transport through the nuclear membrane
10. DEAE-Dextran-mediated transfection of COS cells
11. The subcellular localization of apomucin and nonreducing terminal N-acetylgalactosamine in porcine submaxillary glands
12. Nuclear membrane dynamics and reassembly in living cells: Targeting of an inner nuclear membrane protein in interphase and mitosis
13. Subdomains of the rough endoplasmic reticulum in colon goblet cells of the rat: Lectin-cytochemical characterization
14. The coiled-coil model of alpha-keratin structure
15. Substructure of cisternal organelles of neuronal perikarya in immature rat brains revealed by quick-freeze and deep-etch techniques
16. The ER-Golgi membrane system: Compartmental organization and protein traffic
17. Alpha-helical coiled-coil oligomerization domains in extracellular proteins
18. Tenascin-C hexabrachion assembly is a sequential two-step process initiated by coiled-coil alpha-helices
19. A novel direct interaction of endoplasmic reticulum with microtubules
20. The recycling pathway of protein ERGIC-53 and dynamics of the ER-Golgi intermediate compartment
21. Salt effects on protein stability: Two-stranded alpha-helical coiled-coils containing inter- or intrahelical ion pairs
22. Giantin, a novel conserved Golgi membrane protein containing a cytoplasmic domain of at least 350 kDa
23. Monitoring the dynamics and mobility of membrane proteins tagged with green fluorescent protein
24. Coiled coils: New structures and new functions
25. Prediction and analysis of coiled-coil structures
26. Predicting coiled coils from protein sequences
27. Nucleocytoplasmic transport: The soluble phase
28. Dynamic continuity of nuclear and mitotic matrix proteins in the cell cycle
29. Tropomyosin coiled-coil interactions: Evidence for an unstaggered structure
30. Protein palmitoylation in membrane trafficking
31. Mitosis and inhibition of intracellular transport stimulate palmitoylation of a 62-kD protein
32. Signal transduction from the endoplasmic reticulum to the cell nucleus
33. Movement of nuclei along microtubules in Xenopus egg extracts
34. A visual screen of a GFP-fusion library identifies a new type of nuclear envelope membrane protein
35. Characterization of a novel 63 kDa membrane protein. Implications for the organization of the ER-to-Golgi pathway
36. A reversibly palmitoylated resident protein (p63) of an ER-Golgi intermediate compartment is related to a circulatory shock resuscitation protein
37. Retention of p63 in an ER-Golgi intermediate compartment depends on the presence of all three of its domains and on its ability to form oligomers
38. Determination of the structural requirements for palmitoylation of p63
39. Reassessment of the subcellular localization of p63
40. Intermembrane bridges within membrane organelles revealed by quick-freeze deep-etch electron microscopy
41. A role for the vesicle tethering protein, p115, in the post-mitotic stacking of reassembling Golgi cisternae in a cell-free system
42. The unfolded protein response: An intracellular signaling pathway with many surprising features
43. Human lamin B receptor exhibits sterol C14-reductase activity in Saccharomyces cerevisiae
44. Endoplasmic reticulum: A dynamic patchwork of specialized subregions
45. Coiled coils in both intracellular vesicle and viral membrane fusion
46. Immunolocalization of the insulin regulatable glucose transporter in brown adipose tissue of the rat
47. Amino-acid sequence of rabbit skeletal tropomyosin and its coiled-coil structure
48. A role for giantin in docking COPI vesicles to Golgi membranes
49. Nuclear lamins: Their structure, assembly, and interactions
50. Mobility of cytochrome P450 in the endoplasmic reticulum membrane
51. Getting across the nuclear complex
52. Precursors of chondroitin sulfate proteoglycan are segregated within a subcompartment of the chondrocyte endoplasmic reticulum
53. Membrane tethering in intracellular transport