Quasispecies heterogeneity of the carboxy-terminal part of the E2 gene including the PePHD and sensitivity of hepatitis C virus 1b isolates to antiviral therapy

Virology

Volumn 289, Issue 1, 2001, Pages 150-163

  Sarrazin, Christoph ^a,c   Bruckner, Markus ^a,c   Herrmann, Eva ^b,c   Rüster, Brigitte ^a,c   Bruch, Katharina ^a,c   Roth, W Kurt ^c   Zeuzem, Stefan ^a,c  

^a GOETHE UNIVERSITY   (Germany)

^b DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

^c Inst Transfusionsmedizin I   (Germany)

Author keywords

Double stranded RNA activated protein kinase (PKR) binding domain; Double stranded RNA activated protein kinase (PKR) elF2 phosphorylation homology domain (PePh.D.); Envelope (E)2 protein; Genetic complexity; Genetic diversity; Hepatitis C virus; Nonstructural (NS)5A protein; Secondary structure prediction

Indexed keywords

ANTIVIRUS AGENT; DOUBLE STRANDED RNA; PROTEIN KINASE; RECOMBINANT ALPHA INTERFERON; RIBAVIRIN; VIRUS PROTEIN;

ADULT; AGED; AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CLINICAL ARTICLE; CONFORMATION; DRUG SENSITIVITY; ENZYME BINDING; ENZYME INHIBITION; FEMALE; GENE MUTATION; GENETIC HETEROGENEITY; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; MALE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; SEQUENCE HOMOLOGY; TREATMENT OUTCOME; VIRUS ENVELOPE;

EID: 0035840801     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.2001.1092     Document Type: Article

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