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Volumn 31, Issue 6, 2000, Pages 1360-1370

Mutations within the E2 and NS5A protein in patients infected with hepatitis C virus type 3a and correlation with treatment response

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; COMPLEMENTARY DNA; VIRUS RNA;

EID: 0034116306     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2000.7987     Document Type: Article
Times cited : (65)

References (12)
  • 1
    • 0027068086 scopus 로고
    • The natural history of community-acquired hepatitis C in the United States. The Sentinel Counties Chronic non-A, non-B Hepatitis Study Team
    • Alter MJ, Margolis HS, Krawczynski K, Judson FN, Mares A, Alexander WJ, Hu PY, et al. The natural history of community-acquired hepatitis C in the United States. The Sentinel Counties Chronic non-A, non-B Hepatitis Study Team. N Engl J Med 1992;327:1899-1905.
    • (1992) N Engl J Med , vol.327 , pp. 1899-1905
    • Alter, M.J.1    Margolis, H.S.2    Krawczynski, K.3    Judson, F.N.4    Mares, A.5    Alexander, W.J.6    Hu, P.Y.7
  • 2
    • 0032547938 scopus 로고    scopus 로고
    • Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group
    • McHutchison JG, Gordon SC, Schiff ER, Shiffman ML, Lee WM, Rustgi VK, Goodman ZD, et al. Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group. N Engl J Med 1998;339:H85-1492.
    • (1998) N Engl J Med , vol.339
    • McHutchison, J.G.1    Gordon, S.C.2    Schiff, E.R.3    Shiffman, M.L.4    Lee, W.M.5    Rustgi, V.K.6    Goodman, Z.D.7
  • 3
    • 0032585237 scopus 로고    scopus 로고
    • Randomised trial of Interferon alpha2b plus ribavirin for 48 weeks or for 24 weeks versus interferon alpha2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus
    • International Hepatitis Interventional Therapy Group (IHIT).
    • Poynard T, Marcellin P, Lee SS, Niederau C, Minuk GS, Ideo G, Bain V, et al. Randomised trial of Interferon alpha2b plus ribavirin for 48 weeks or for 24 weeks versus interferon alpha2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. International Hepatitis Interventional Therapy Group (IHIT). Lancet 1998;352:1426-1432.
    • (1998) Lancet , vol.352 , pp. 1426-1432
    • Poynard, T.1    Marcellin, P.2    Lee, S.S.3    Niederau, C.4    Minuk, G.S.5    Ideo, G.6    Bain, V.7
  • 5
    • 0344765507 scopus 로고    scopus 로고
    • Repression of the PKR protein kinase by the hepatitis C virus NS5A protein: A potential mechanism of interferon resistance
    • Gale MJ, Jr., Korth MJ, Katze MG. Repression of the PKR protein kinase by the hepatitis C virus NS5A protein: a potential mechanism of interferon resistance. Clin Diagn Virol 1998;10:157-162.
    • (1998) Clin Diagn Virol , vol.10 , pp. 157-162
    • Gale Jr., M.J.1    Korth, M.J.2    Katze, M.G.3
  • 6
    • 17144463221 scopus 로고    scopus 로고
    • Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: Molecular mechanisms of kinase regulation
    • Gale M, Jr., Blakely CM, Kwieciszewski B, Tan SL, Dossett M, Tang NM, Korth MJ, et al. Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation. Mol Cell Biol 1998;18:5208-5218.
    • (1998) Mol Cell Biol , vol.18 , pp. 5208-5218
    • Gale Jr., M.1    Blakely, C.M.2    Kwieciszewski, B.3    Tan, S.L.4    Dossett, M.5    Tang, N.M.6    Korth, M.J.7
  • 7
    • 0343924357 scopus 로고    scopus 로고
    • Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein
    • Gale MJ, Jr., Korth MJ, Tang NM, Tan SL, Hopkins DA, Dever TE, Polyak SJ, et al. Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein. Virology 1997;230:217-227.
    • (1997) Virology , vol.230 , pp. 217-227
    • Gale Jr., M.J.1    Korth, M.J.2    Tang, N.M.3    Tan, S.L.4    Hopkins, D.A.5    Dever, T.E.6    Polyak, S.J.7
  • 8
    • 9144257569 scopus 로고    scopus 로고
    • Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus Ib infection
    • Enomoto N, Sakuma I, Asahina V, Kurosaki M, Murakami T, Yamamoto C, Ogura Y, et al. Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus Ib infection. N Engl J Med 1996;334:77-81.
    • (1996) N Engl J Med , vol.334 , pp. 77-81
    • Enomoto, N.1    Sakuma, I.2    Asahina, V.3    Kurosaki, M.4    Murakami, T.5    Yamamoto, C.6    Ogura, Y.7
  • 9
    • 0034101768 scopus 로고    scopus 로고
    • Mutations in the protein kinase-binding domain of the NS5A protein in patients infected with hepatitis C virus type la are associated with treatment response
    • Sarrazin C, Berg T, Lee JH, Rüster B, Kronenberger B, Roth WK, Zeuzem S. Mutations in the protein kinase-binding domain of the NS5A protein in patients infected with hepatitis C virus type la are associated with treatment response. J Infect Dis 2000;181:432-441.
    • (2000) J Infect Dis , vol.181 , pp. 432-441
    • Sarrazin, C.1    Berg, T.2    Lee, J.H.3    Rüster, B.4    Kronenberger, B.5    Roth, W.K.6    Zeuzem, S.7
  • 10
    • 0031050892 scopus 로고    scopus 로고
    • Pretreatment virus load and multiple amino acid substitutions in the interferon sensitivity-determining region predict the outcome of interferon treatment in patients with chronic genotype Ib hepatitis C virus infection
    • Chayama K, Tsubota A, Kobayashi M, Okamoto K, Hashimoto M, Miyano Y, Koike H, et al. Pretreatment virus load and multiple amino acid substitutions in the interferon sensitivity-determining region predict the outcome of interferon treatment in patients with chronic genotype Ib hepatitis C virus infection. HEPATOLOGY 1997;25:745-749.
    • (1997) Hepatology , vol.25 , pp. 745-749
    • Chayama, K.1    Tsubota, A.2    Kobayashi, M.3    Okamoto, K.4    Hashimoto, M.5    Miyano, Y.6    Koike, H.7
  • 11
    • 0031042869 scopus 로고    scopus 로고
    • Analysis of genotypes and amino acid residues 2209 to 2248 of the NS5A region of hepatitis C virus in relation to the response to interferon-beta therapy
    • Kurosaki M, Enomoto N, Murakami T, Sakuma I, Asahina Y, Yamamoto C, Ikeda T, et al. Analysis of genotypes and amino acid residues 2209 to 2248 of the NS5A region of hepatitis C virus in relation to the response to interferon-beta therapy. HEPATOLOGY 1997;25:750-753.
    • (1997) Hepatology , vol.25 , pp. 750-753
    • Kurosaki, M.1    Enomoto, N.2    Murakami, T.3    Sakuma, I.4    Asahina, Y.5    Yamamoto, C.6    Ikeda, T.7
  • 12
    • 0031433238 scopus 로고    scopus 로고
    • Mutations in the nonstructural protein 5A gene and response to interferon therapy in young patients with chronic hepatitis C virus 1b infection
    • Komatsu H, Fujisawa T, Inui A, Miyagawa Y, Onoue M. Mutations in the nonstructural protein 5A gene and response to interferon therapy in young patients with chronic hepatitis C virus 1b infection. J Med Virol 1997;53:361-365.
    • (1997) J Med Virol , vol.53 , pp. 361-365
    • Komatsu, H.1    Fujisawa, T.2    Inui, A.3    Miyagawa, Y.4    Onoue, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.