-
1
-
-
0028267240
-
Camptothecins from bench research to hospital wards
-
Potmesil M: Camptothecins from bench research to hospital wards. Cancer Res 54:1431-1439, 1994
-
(1994)
Cancer Res
, vol.54
, pp. 1431-1439
-
-
Potmesil, M.1
-
2
-
-
0028350106
-
Topoisomerase I inhibitors: An overview of the camptothecin analogs
-
Burris HA, Fields SM: Topoisomerase I inhibitors: An overview of the camptothecin analogs. Hematol Oncol Clin North Am 8:333-355, 1994
-
(1994)
Hematol Oncol Clin North Am
, vol.8
, pp. 333-355
-
-
Burris, H.A.1
Fields, S.M.2
-
3
-
-
0000760112
-
The Camptothecins
-
Chabner BA, Longo DL (eds): Philadelphia, PA, Lippincott-Raven
-
Takimoto CH, Arbuck SG: The Camptothecins, in Chabner BA, Longo DL (eds): Cancer Chemotherapy and Biotherapy: Principles and Practice (ed 2). Philadelphia, PA, Lippincott-Raven, 1996, pp 463-484
-
(1996)
Cancer Chemotherapy and Biotherapy: Principles and Practice (Ed 2)
, pp. 463-484
-
-
Takimoto, C.H.1
Arbuck, S.G.2
-
4
-
-
0024358188
-
DNA topoisomerase-targeted chemotherapy of human colon cancer in xenografts
-
Giovanella BC, Stehlin JS, Wall ME, et al: DNA topoisomerase-targeted chemotherapy of human colon cancer in xenografts. Science 246:1046-1048, 1989
-
(1989)
Science
, vol.246
, pp. 1046-1048
-
-
Giovanella, B.C.1
Stehlin, J.S.2
Wall, M.E.3
-
5
-
-
0026694680
-
Complete inhibition of growth followed by death of human malignant melanoma cells in vitro and regression of human melanoma xenografts in immunodeficient mice induced by camptothecins
-
Pantazis P, Hinz HR, Mendoza JT, et al: Complete inhibition of growth followed by death of human malignant melanoma cells in vitro and regression of human melanoma xenografts in immunodeficient mice induced by camptothecins. Cancer Res 52:3980-3987, 1992
-
(1992)
Cancer Res
, vol.52
, pp. 3980-3987
-
-
Pantazis, P.1
Hinz, H.R.2
Mendoza, J.T.3
-
6
-
-
0028904703
-
A phase I and pharmacokinetic study of a new camptothecin derivative, 9-aminocamptothecin
-
Rubin E, Wood V, Bharti A, et al: A phase I and pharmacokinetic study of a new camptothecin derivative, 9-aminocamptothecin. Clin Cancer Res 1:269-276, 1995
-
(1995)
Clin Cancer Res
, vol.1
, pp. 269-276
-
-
Rubin, E.1
Wood, V.2
Bharti, A.3
-
7
-
-
9244231199
-
A phase I and pharmacologic study of 9-aminocamptothecin given by 72-hour infusion in adult cancer patients
-
Dahut W, Harold N, Takimoto C, et al: A phase I and pharmacologic study of 9-aminocamptothecin given by 72-hour infusion in adult cancer patients. J Clin Oncol 14:1236-1244, 1996
-
(1996)
J Clin Oncol
, vol.14
, pp. 1236-1244
-
-
Dahut, W.1
Harold, N.2
Takimoto, C.3
-
8
-
-
84871465632
-
A phase II and dose escalation study ± G-CSF of 9-amino-camptothecin (9-AC) in relapsed lymphoma
-
abstr
-
Wilson WH, Pearson D, Humphrey R, et al: A phase II and dose escalation study ± G-CSF of 9-amino-camptothecin (9-AC) in relapsed lymphoma. Ann Oncol 7:131, 1996 (suppl 7; abstr)
-
(1996)
Ann Oncol
, vol.7
, Issue.7 SUPPL.
, pp. 131
-
-
Wilson, W.H.1
Pearson, D.2
Humphrey, R.3
-
9
-
-
0024537205
-
Modification of the hydroxy lactone ring of camptothecins: Inhibition of mammalian topoisomerase I and biological activity
-
Hertzberg RP, Caranfa MJ, Holden, et al: Modification of the hydroxy lactone ring of camptothecins: Inhibition of mammalian topoisomerase I and biological activity. J Med Chem 32:715-720, 1989
-
(1989)
J Med Chem
, vol.32
, pp. 715-720
-
-
Hertzberg, R.P.1
Caranfa, M.J.2
Holden3
-
10
-
-
0027096415
-
A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues
-
Fassberg J, Stella VJ: A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues. J Pharm Sci 81:676-684, 1992
-
(1992)
J Pharm Sci
, vol.81
, pp. 676-684
-
-
Fassberg, J.1
Stella, V.J.2
-
11
-
-
0028256230
-
Analysis of the active lactone form of 9-aminocamptothecin in plasma using solid-phase extraction and high-performance liquid chromatography
-
Takimoto CH, Klecker RW, Dahut WL, et al: Analysis of the active lactone form of 9-aminocamptothecin in plasma using solid-phase extraction and high-performance liquid chromatography. J ChromatogrB Biomed Appl 655:97-104, 1994
-
(1994)
J ChromatogrB Biomed Appl
, vol.655
, pp. 97-104
-
-
Takimoto, C.H.1
Klecker, R.W.2
Dahut, W.L.3
-
12
-
-
0028022585
-
Metabolic fate of irinotecan in humans: Correlation of glucuronidation with diarrhea
-
Gupta E, Letingi TM, Mick R, et al: Metabolic fate of irinotecan in humans: Correlation of glucuronidation with diarrhea. Cancer Res 54:3723-3725, 1994
-
(1994)
Cancer Res
, vol.54
, pp. 3723-3725
-
-
Gupta, E.1
Letingi, T.M.2
Mick, R.3
-
13
-
-
0004277838
-
-
New York, NY, Dekker
-
Gibaldi M, Perrier D: Pharmacokinetics (ed 2). New York, NY, Dekker, 1982, p 321
-
(1982)
Pharmacokinetics (Ed 2)
, pp. 321
-
-
Gibaldi, M.1
Perrier, D.2
-
14
-
-
0019974468
-
Noncompartmental determination of the steady-state volume of distribution for any mode of administration
-
Perrier D, Mayersohn M: Noncompartmental determination of the steady-state volume of distribution for any mode of administration. J Pharm Sci 71:372-373, 1982
-
(1982)
J Pharm Sci
, vol.71
, pp. 372-373
-
-
Perrier, D.1
Mayersohn, M.2
-
15
-
-
28444434356
-
-
San Francisco, CA, University of California, San Francisco
-
Beal SL, Sheiner LB: NONMEM Project Group (ed 2.1). San Francisco, CA, University of California, San Francisco, 1989
-
(1989)
NONMEM Project Group (Ed 2.1)
-
-
Beal, S.L.1
Sheiner, L.B.2
-
16
-
-
0003403775
-
-
Philadelphia, PA, Williams & Wilkins
-
Rowland M, Tozer T: Clinical Pharmacokinetics: Concepts and Applications (ed 3). Philadelphia, PA, Williams & Wilkins, 1995, p 173
-
(1995)
Clinical Pharmacokinetics: Concepts and Applications (Ed 3)
, pp. 173
-
-
Rowland, M.1
Tozer, T.2
-
17
-
-
0014895176
-
Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC-100880)
-
Gottlieb JA, Guarino AM, Call JB, et al: Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC-100880). Cancer Chemother Rep 54:461-470, 1970
-
(1970)
Cancer Chemother Rep
, vol.54
, pp. 461-470
-
-
Gottlieb, J.A.1
Guarino, A.M.2
Call, J.B.3
-
18
-
-
0003403775
-
-
Philadelphia, PA, Williams & Wilkins
-
Rowland M, Tozer T: Clinical Pharmacokinetics: Concepts and Applications (ed 3). Philadelphia, PA, Williams & Wilkins, 1995, p 341
-
(1995)
Clinical Pharmacokinetics: Concepts and Applications (Ed 3)
, pp. 341
-
-
Rowland, M.1
Tozer, T.2
-
19
-
-
0028130504
-
Clinical pharmacodynamics of continuous infusion topotecan in children: Systemic exposure predicts hematologic toxicity
-
Stewart CF, Baker SD, Heideman RL, et al: Clinical pharmacodynamics of continuous infusion topotecan in children: Systemic exposure predicts hematologic toxicity. J Clin Oncol 12:1946-1954, 1994
-
(1994)
J Clin Oncol
, vol.12
, pp. 1946-1954
-
-
Stewart, C.F.1
Baker, S.D.2
Heideman, R.L.3
-
20
-
-
0027184132
-
Ethyl substitution at the 7 position extends the half-life of 10-hydroxycamptothecin in the presence of human serum albumin
-
Burke TG, Mi Z: Ethyl substitution at the 7 position extends the half-life of 10-hydroxycamptothecin in the presence of human serum albumin. J Med Chem 36:2580-2582, 1993
-
(1993)
J Med Chem
, vol.36
, pp. 2580-2582
-
-
Burke, T.G.1
Mi, Z.2
-
21
-
-
0027407637
-
Pediatric phase I trial and pharmacokinetic study of topotecan administered as a 24-hour continuous infusion
-
Blaney SM, Balis FM, Cole DE, et al: Pediatric phase I trial and pharmacokinetic study of topotecan administered as a 24-hour continuous infusion. Cancer Res 53:1032-1036, 1993
-
(1993)
Cancer Res
, vol.53
, pp. 1032-1036
-
-
Blaney, S.M.1
Balis, F.M.2
Cole, D.E.3
-
22
-
-
0028158012
-
Phase I and pharmacological study of the novel topoisomerase I inhibitor 7-ethyl-10-[4-(1-piperdino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) administered as a 90 minute infusion every 3 weeks
-
Rowinsky EK, Grochow LB, Ettinger DS, et al: Phase I and pharmacological study of the novel topoisomerase I inhibitor 7-ethyl-10-[4-(1-piperdino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) administered as a 90 minute infusion every 3 weeks. Cancer Res 54:427-436, 1994
-
(1994)
Cancer Res
, vol.54
, pp. 427-436
-
-
Rowinsky, E.K.1
Grochow, L.B.2
Ettinger, D.S.3
-
23
-
-
0027140524
-
Phase I and pharmacokinetic trial of weekly CPT-11
-
Rothenberg ML, Kuhn JG, Burris HA, et al: Phase I and pharmacokinetic trial of weekly CPT-11. J Clin Oncol 11:2194-2204, 1993
-
(1993)
J Clin Oncol
, vol.11
, pp. 2194-2204
-
-
Rothenberg, M.L.1
Kuhn, J.G.2
Burris, H.A.3
-
24
-
-
0028670840
-
Kinetics of the in vivo interconversion of the carboxylate and lactone forms of irinotecan (CPT-11) and of its metabolite SN-38 in patients
-
Rivory LP, Chateleut E, Canal P, et al: Kinetics of the in vivo interconversion of the carboxylate and lactone forms of irinotecan (CPT-11) and of its metabolite SN-38 in patients. Cancer Res 54:6330-6333, 1994
-
(1994)
Cancer Res
, vol.54
, pp. 6330-6333
-
-
Rivory, L.P.1
Chateleut, E.2
Canal, P.3
-
25
-
-
0026537874
-
Phase I and pharmacologic study of topotecan: A novel topoisomerase I inhibitor
-
Rowinsky EK, Grochow LB, Hendricks CB, et al: Phase I and pharmacologic study of topotecan: A novel topoisomerase I inhibitor. J Clin Oncol 10:647-656, 1992
-
(1992)
J Clin Oncol
, vol.10
, pp. 647-656
-
-
Rowinsky, E.K.1
Grochow, L.B.2
Hendricks, C.B.3
-
26
-
-
0026646768
-
Pharmacokinetics and pharmacodynamics of topotecan in patients with advanced cancer
-
Grochow LB, Rowinsky EK, Johnson R, et al: Pharmacokinetics and pharmacodynamics of topotecan in patients with advanced cancer. Drug Metab Disp 20:706-713, 1992
-
(1992)
Drug Metab Disp
, vol.20
, pp. 706-713
-
-
Grochow, L.B.1
Rowinsky, E.K.2
Johnson, R.3
|