A yeast homolog of the mammalian mannose 6-phosphate receptors contributes to the sorting of vacuolar hydrolases

Current Biology

Volumn 11, Issue 13, 2001, Pages 1074-1078

  Whyte, James R C ^a   Munro, Sean ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYPEPTIDASE; CELL MEMBRANE TRANSPORT; CELL VACUOLE; ENDOSOME; FUNGAL ENZYME; GENE DELETION; GOLGI COMPLEX; HYDROLASE; MOLECULAR RECOGNITION; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE; SOMATOMEDIN B RECEPTOR;

EID: 0035838461     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00273-1     Document Type: Article

References (22)

1. The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene
2. Multiple sorting pathways between the late Golgi and the vacuole in yeast
3. Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors
4. The MRH domain suggests a shared ancestry for the mannose 6-phosphate receptors and other N-glycan recognizing proteins
5. Vps10p cycles between the late-Golgi and prevacuolar compartments in its function as the sorting receptor for multiple yeast vacuolar hydrolases
6. The cytoplasmic tail domain of the vacuolar protein sorting receptor Vps10p and a subset of VPS gene products regulate receptor stability, function, and localization
7. Multiple pathways for vacuolar sorting of yeast proteinase A
8. Biogenesis of the yeast vacuole (lysosome). Proteinase yscB contributes molecularly and kinetically to vacuolar hydrolase-precursor maturation
9. Vacuolar and extracellular maturation of Saccharomyces cerevisiae proteinase A
10. Autoactivation of proteinase A initiates activation of yeast vacuolar zymogens
11. Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products
12. Processing pathway for protease B of Saccharomyces cerevisiae
13. Vps1p, a member of the dynamin GTPase family, is necessary for Golgi membrane protein retention in Saccharomyces cerevisiae
14. Protein sorting in yeast: Mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway
15. Protein sorting in Saccharomyces cerevisiae: Isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases
16. Carbohydrate chains on yeast carboxypeptidase Y are phosphorylated
17. Characterization of proteinase A glycoforms from recombinant Saccharomyces cerevisiae
18. Cloning and characterization of the ALG3 gene of Saccharomyces cerevisiae
19. Mannose 6-phosphate-independent targeting of lysosomal enzymes in I-cell disease B lymphoblasts
20. Localization of the insulin-like growth factor II binding site to amino acids 1508-1566 in repeat 11 of the mannose 6-phosphate/insulin-like growth factor II receptor
21. Mannose 6-phosphate/insulin-like growth factor-II receptor targets the urokinase receptor to lysosomes via a novel binding interaction
22. Heterologous HIS3 marker and GFP reporter modules for PCR-targeting in Saccharomyces cerevisiae