Paradoxical effects of trichostatin A: Inhibition of NF-Y-associated histone acetyltransferase activity, phosphorylation of hGCN5 and downregulation of cyclin A and B1 mRNA

Cancer Letters

Volumn 166, Issue 1, 2001, Pages 55-64

  Nair, A R ^a   Boersma, L J ^a   Schiltz, L ^b   Chaudry, A ^c   Muschel, R J ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Cyclin B; Histone acetyltransferase; Trichostatin A

Indexed keywords

CYCLIN A; CYCLIN B1; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE GCN5; HISTONE DEACETYLASE; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSRIPTION FACTOR NF Y; TRICHOSTATIN A; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HELA CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; UTERINE CERVIX CARCINOMA;

ACETYLTRANSFERASES; CCAAT-BINDING FACTOR; CELL CYCLE PROTEINS; CYCLIN A; CYCLIN B; DOWN-REGULATION; ENZYME INHIBITORS; HELA CELLS; HISTONE ACETYLTRANSFERASES; HUMANS; HYDROXAMIC ACIDS; PHOSPHORYLATION; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0035837658     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(01)00418-9     Document Type: Article

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