Mice disrupted for the KvLQT1 potassium channel regulator IsK gene accumulate mature T cells

Cellular Immunology

Volumn 209, Issue 1, 2001, Pages 1-9

  Chabannes, Dominique ^a   Barhanin, Jacques ^b   Escande, Denis ^a  

^a HÔTEL DIEU   (France)

^b INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

KCNE1; KCNQ1; Potassium channels; T cell homeostasis; Thymus

Indexed keywords

POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; GENE DISRUPTION; GENE EXPRESSION; GENE MUTATION; HEART REPOLARIZATION; HOMEOSTASIS; LONG QT SYNDROME; MOUSE; NONHUMAN; PHENOTYPE; POTASSIUM CURRENT; PRIORITY JOURNAL; SUDDEN DEATH; T LYMPHOCYTE; TANDEM REPEAT; THYMUS;

MURINAE;

EID: 0035836409     PISSN: 00088749     EISSN: None     Source Type: Journal    
DOI: 10.1006/cimm.2001.1780     Document Type: Article

References (28)

1. K(V)LQT1 and IsK (minK) proteins associate to form the I(Ks) cardiac potassium current
2. Coassembly of K(V)-LQT1 and mink (IsK) proteins to form cardiac I(Ks) potassium channel
3. Mutations in Hmink gene cause long QT syndrome and supress IKs function
4. Positional cloning of a novel potassium channel gene: KVLQT 1 mutations cause cardiac arrhythmias
5. Differential expression of KvLQT1 and its regulator IsK in mouse epithelia
6. Inner ear defects induced by null mutation of the IsK gene
7. IsK and KvLQT1: Mutation in either of the two subunits of the slow component of the delayed rectifier potassium channel can cause Jervell and Lange-Nielsen syndrome
8. Cloning, functional expression and regulation of two K+ channels in human T lymphocytes
9. The thymic microenvironment
10. Development in the thymus: It takes two to tango
11. Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes
12. Simultaneous isolation of preparative amounts of RNA and DNA from Trichinella spiralis by cesium trifluoroacetate isopycnic centrifugation
13. Expression and functional significance of the J11d marker on mouse thymocytes
14. Activation and interaction of CD44 and hyaluronan in immunological system
15. T cell activation via Leu-23 (CD69)
16. Inhibition of thymocyte apoptosis and negative antigenic selection in bcl-2 transgenic mice
17. An activated form of Notch influences the choice between CD4 and CD8 T cell lineages
18. Correlating Notch signaling with thymocyte maturation
19. Differential requirements for survival and proliferation of CD8 naive or memory T cells
20. Sodium and potassium channels in epithelial cells from thymus glands and thymomas of myasthenia gravis patients
21. The application of in vitro isolation, cryopreservation and patch-clamp microelectrode recording methods to adult rat thymic nurse cells
22. A minK-HERG complex regulates the cardiac potassium current I(Kr)
23. Tissue and species distribution of mRNA for the IKr-like K+ channel erg
24. Blockade of the voltage-gated potassium channel Kv1.3 inhibits immune responses in vivo
25. Identification of Kv1.1 expression by murine CD4-CD8- thymocytes. A role for voltage-dependent K+ channels in murine thymocyte development
26. Evidence for voltage modulation of IL2 production in mitogen-stimulated human peripheral blood lymphocytes
27. Voltage-gated potassium channels regulate calcium-dependent pathways involved in human T lymphocyte activation
28. Ion channels, Ca2+ signaling and reporter gene expression in antigen-specific mouse T cells