Identification of the Bile Acid-binding Site of the Ileal Lipid-binding Protein by Photoaffinity Labeling, Matrix-assisted Laser Desorption Ionization-Mass Spectrometry, and NMR Structure

Journal of Biological Chemistry

Volumn 276, Issue 10, 2001, Pages 7291-7301

  Kramer, Werner ^a   Sauber, Klaus ^b   Baringhaus, Karl Heinz ^b   Kurz, Michael ^b   Stengelin, Siegfried ^b   Lange, Gudrun ^b   Corsiero, Daniel ^b   Girbig, Frank ^b   König, Waltraud ^b   Weyland, Claudia ^b  

^a SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROPHORESIS; LIPIDS; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; ORGANIC ACIDS; PROTEINS;

FRAGMENTATION;

BIOCHEMISTRY;

2 (3,3 AZO 7ALPHA,12ALPHA DIHYDROXY 5BETA CHOLAN 24 OYLAMINO)ETHANESULFONIC ACID; 2 (7,7 AZO 3ALPHA,12ALPHA DIHYDROXY 5BETA CHOLAN 24 OYLAMINO)ETHANESULFONIC ACID; AZO COMPOUND; BILE ACID; HISTIDINE; ILEAL LIPID BINDING PROTEIN; LIPID BINDING PROTEIN; PHENYLGLYOXAL; PROTEINASE; SERINE; TAUROCHOLIC ACID; THREONINE; TRYPSIN; UNCLASSIFIED DRUG; ARGININE; CARRIER PROTEIN; CHOLAGOGUE; COTRANSPORTER; ORGANIC ANION TRANSPORTER; RECOMBINANT PROTEIN; SODIUM BILE ACID COTRANSPORTER; SODIUM-BILE ACID COTRANSPORTER;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENTEROHEPATIC CIRCULATION; GEL ELECTROPHORESIS; ILEUM; INTESTINE ABSORPTION; INTESTINE CELL; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PHOTOAFFINITY LABELING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN MODIFICATION; RABBIT; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DNA SEQUENCE; HUMAN; IMMUNOBLOTTING; MASS SPECTROMETRY; METABOLISM; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; SEQUENCE HOMOLOGY;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

AMINO ACID SEQUENCE; ANIMALS; ARGININE; BILE ACIDS AND SALTS; BINDING SITES; CARRIER PROTEINS; CHOLAGOGUES AND CHOLERETICS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HISTIDINE; HUMANS; IMMUNOBLOTTING; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; PHENYLGLYOXAL; PHOTOAFFINITY LABELS; PROTEIN BINDING; RABBITS; RECOMBINANT PROTEINS; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SERINE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SYMPORTERS; TAUROCHOLIC ACID; THREONINE;

EID: 0035831545     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M006877200     Document Type: Article

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