Expression and purification of human recombinant GST-FGF receptor-1

Journal of Biotechnology

Volumn 86, Issue 1, 2001, Pages 51-58

  Homann, Stefanie ^a   Schacher, Barbara ^a   Zumstein Mecker, Sabine ^a   Fabbro, Doriano ^a   Bold, Guido ^a   Ferrari, Stefano ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Baculovirus; Expression; FGFR 1; Purification

Indexed keywords

ADENOSINE TRIPHOSPHATE; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 1; MONOCLONAL ANTIBODY; PHOSPHOTRANSFERASE; PROTEIN TYROSINE KINASE INHIBITOR; TYROSINE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CANCER GROWTH; CANCER INVASION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME MECHANISM; ENZYME PURIFICATION; HUMAN; HUMAN CELL; METASTASIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIBODIES, MONOCLONAL; BACULOVIRIDAE; BINDING SITES; ENZYME INHIBITORS; ENZYME STABILITY; FIBROBLAST GROWTH FACTOR 1; FREEZING; GENE EXPRESSION; GLUTATHIONE TRANSFERASE; HUMANS; KINETICS; PHOSPHORYLATION; PHOSPHOTYROSINE; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECEPTORS, FIBROBLAST GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; SPODOPTERA; SUBSTRATE SPECIFICITY;

UNIDENTIFIED BACULOVIRUS;

EID: 0035831348     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-1656(00)00399-0     Document Type: Article

References (22)

1. Vascular development: Cellular and molecular regulation
2. Inhibitory activity and selectivity of staurosporine derivatives towards protein kinase C
3. Proteolytic activity in infected and non-infected insect cells: Degradation of HIV-1 Pr55gag particles
4. Homogeneous purification of human recombinant GST-Akt/PKB from Sf9 cells
5. Inhibitors of protein kinases: CGP 41251 a protein kinase inhibitor with potential as an anticancer agent
6. Angiogenesis inhibitors generated by tumors
7. Blood vessel formation: What is its molecular basis?
8. Activation of PKC subytpes α, γ, δ, ε, ζ and η by tumor promoting and non-tumor promoting agents
9. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
10. New model of tumor angiogenesis: Dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF
11. s6k produced as a function of the infectious response
12. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
13. Protein kinase C and mammary cell differentiation: An essential role for PKC-α in the induction of β-casein expression
14. Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction
15. Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism
16. Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain
17. In vitro biological characterization and antiangiogenic effects of PD 166866, a selective inhibitor of the FGF-1 receptor tyrosine kinase
18. How do protein kinases recognize their substrates?
19. Tumor-associated angiogenesis: Mechanisms, clinical implications, and therapeutic strategies
20. Use of synthetic amino acid polymers for assay of protein-tyrosine and protein-serine kinases
21. Fibroblast growth factors as multifunctional signaling factors
22. Cancer dormancy: Opportunities for new therapeutic approaches