메뉴 건너뛰기




Volumn 286, Issue 1, 1998, Pages 569-577

In vitro biological characterization and antiangiogenic effects of PD 166866, a selective inhibitor of the FGF-1 receptor tyrosine kinase

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR; INSULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PD 166866; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 0031821631     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (76)

References (36)
  • 3
    • 0027360010 scopus 로고
    • Distinct patterns of expression of fibroblast growth factors and their receptors in human atheroma and nonatherosclerotic arteries: Association of acidic FGF with plaque microvessels and macrophages
    • Brogi E, Winkles JA, Underwood R, Clinton SK, Alberts GF and Libby P (1993) Distinct patterns of expression of fibroblast growth factors and their receptors in human atheroma and nonatherosclerotic arteries: Association of acidic FGF with plaque microvessels and macrophages. J Clin Invest 92:2408-2418.
    • (1993) J Clin Invest , vol.92 , pp. 2408-2418
    • Brogi, E.1    Winkles, J.A.2    Underwood, R.3    Clinton, S.K.4    Alberts, G.F.5    Libby, P.6
  • 5
    • 0028968622 scopus 로고
    • Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class
    • Buchdunger E, Zimmermann J, Mett H, Meyer T, Muller M, Regenass U and Lydon N (1995) Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class. Proc Natl Acad Sci USA 92:2258-2262.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2258-2262
    • Buchdunger, E.1    Zimmermann, J.2    Mett, H.3    Meyer, T.4    Muller, M.5    Regenass, U.6    Lydon, N.7
  • 6
    • 0026578427 scopus 로고
    • Protein-tyrosine kinase inhibitors
    • Burke TR (1992) Protein-tyrosine kinase inhibitors. Drugs Future 17:119-131.
    • (1992) Drugs Future , vol.17 , pp. 119-131
    • Burke, T.R.1
  • 7
    • 0026510966 scopus 로고
    • Receptor tyrosine kinases
    • Cadena DL and Gill GN (1992) Receptor tyrosine kinases. FASEB J 6:2332-2337.
    • (1992) FASEB J , vol.6 , pp. 2332-2337
    • Cadena, D.L.1    Gill, G.N.2
  • 8
    • 0018735516 scopus 로고
    • Statistical analysis of enzyme kinetic data
    • Cleland WW (1979) Statistical analysis of enzyme kinetic data. Methods Enzymol 63:103-112.
    • (1979) Methods Enzymol , vol.63 , pp. 103-112
    • Cleland, W.W.1
  • 12
    • 0022123620 scopus 로고
    • Toward an understanding of angiogenesis: Search and discovery
    • Folkman J (1985) Toward an understanding of angiogenesis: Search and discovery. Perspect Biol Med 29:10-36.
    • (1985) Perspect Biol Med , vol.29 , pp. 10-36
    • Folkman, J.1
  • 13
    • 0023157363 scopus 로고
    • Angiogenic factors
    • Folkman J and Klagsbrun M (1987) Angiogenic factors. Science 235:442-447.
    • (1987) Science , vol.235 , pp. 442-447
    • Folkman, J.1    Klagsbrun, M.2
  • 14
    • 0029143960 scopus 로고
    • Molecular mechanisms of angiogenesis: Fibroblast growth factor signal transduction
    • Friesel R and Maciag T (1995) Molecular mechanisms of angiogenesis: Fibroblast growth factor signal transduction. FASEB J 9:919-925.
    • (1995) FASEB J , vol.9 , pp. 919-925
    • Friesel, R.1    Maciag, T.2
  • 17
    • 0026649742 scopus 로고
    • Fibroblast growth factor receptor tyrosine kinases: Molecular analysis and signal transduction
    • Jaye M, Schlessinger J and Dionne CA (1992) Fibroblast growth factor receptor tyrosine kinases: molecular analysis and signal transduction. Biochem Biophys Acta 1135:185-199.
    • (1992) Biochem Biophys Acta , vol.1135 , pp. 185-199
    • Jaye, M.1    Schlessinger, J.2    Dionne, C.A.3
  • 18
    • 0026461137 scopus 로고
    • Characterization of baculovirus-expressed human α and β platelet-derived growth factor receptors
    • Jensen RA, Beeler JF, Heidaran MA and LaRochelle WJ (1992) Characterization of baculovirus-expressed human α and β platelet-derived growth factor receptors. Biochemistry 31:10887-10892.
    • (1992) Biochemistry , vol.31 , pp. 10887-10892
    • Jensen, R.A.1    Beeler, J.F.2    Heidaran, M.A.3    LaRochelle, W.J.4
  • 21
    • 0026451516 scopus 로고
    • A cascade model for restenosis: A special case of atherosclerosis progression
    • Libby P, Schwartz D, Brogi E, Tanaka H and Clinton SK (1992) A cascade model for restenosis: A special case of atherosclerosis progression. Circulation 86:47-52.
    • (1992) Circulation , vol.86 , pp. 47-52
    • Libby, P.1    Schwartz, D.2    Brogi, E.3    Tanaka, H.4    Clinton, S.K.5
  • 22
    • 0024385914 scopus 로고
    • Tyrphostins inhibit epidermal growth factor (EGF)-receptor tyrosine kinase activity in living cells and EGF-stimulated cell proliferation
    • Lyall RM, Zilberstein A, Gazit A, Gilon C, Levitzki A and Schlessinger J (1989) Tyrphostins inhibit epidermal growth factor (EGF)-receptor tyrosine kinase activity in living cells and EGF-stimulated cell proliferation. J Biol Chem 264:14503-14509.
    • (1989) J Biol Chem , vol.264 , pp. 14503-14509
    • Lyall, R.M.1    Zilberstein, A.2    Gazit, A.3    Gilon, C.4    Levitzki, A.5    Schlessinger, J.6
  • 23
    • 0030027488 scopus 로고    scopus 로고
    • Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction
    • Mohammadi M, Dikic I, Sorokin A, Burgess WH, Jaye M and Schlessinger J (1996) Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction. Mol Cell Biol 16:977-989.
    • (1996) Mol Cell Biol , vol.16 , pp. 977-989
    • Mohammadi, M.1    Dikic, I.2    Sorokin, A.3    Burgess, W.H.4    Jaye, M.5    Schlessinger, J.6
  • 24
    • 0030945871 scopus 로고    scopus 로고
    • Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors
    • Mohammadi M, McMahon G, Sun L, Tang C, Hirth P, Yeh B, Hubbard S and Schlessinger J (1997) Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science 276:955-960.
    • (1997) Science , vol.276 , pp. 955-960
    • Mohammadi, M.1    McMahon, G.2    Sun, L.3    Tang, C.4    Hirth, P.5    Yeh, B.6    Schlessinger J, H.S.7
  • 25
    • 0025609724 scopus 로고
    • Inhibition of tyrosine kinase and epidermal growth factor receptor internalization by lavendustin: A methyl ester in cultured A431 cells
    • Onoda T, Ishiki K, Takeuchi T, Tatsuta K and Umezawa K (1990) Inhibition of tyrosine kinase and epidermal growth factor receptor internalization by lavendustin: A methyl ester in cultured A431 cells. Drugs Expt Clin Res 16:249-253.
    • (1990) Drugs Expt Clin Res , vol.16 , pp. 249-253
    • Onoda, T.1    Ishiki, K.2    Takeuchi, T.3    Tatsuta, K.4    Umezawa, K.5
  • 26
    • 0027570012 scopus 로고
    • The assembly of signaling complexes by receptor tyrosine kinases
    • Panayotou G and Waterfield MD (1993) The assembly of signaling complexes by receptor tyrosine kinases. Bioessays 15:171-177.
    • (1993) Bioessays , vol.15 , pp. 171-177
    • Panayotou, G.1    Waterfield, M.D.2
  • 28
    • 0015097243 scopus 로고
    • The smooth muscle cell. II. Growth of smooth muscle in culture and formation of elastic fibers
    • Ross R (1971) The smooth muscle cell. II. Growth of smooth muscle in culture and formation of elastic fibers. J Cell Biol 50:172-186.
    • (1971) J Cell Biol , vol.50 , pp. 172-186
    • Ross, R.1
  • 30
    • 0028273336 scopus 로고
    • Tyrosine kinase inhibitors. 2. Synthesis of 2,2′-dithiobis(1H-indole-3-alkanmides) and investigation of their inhibitory activity against epidermal growth factor receptor and pp60v-src protein tyrosine kinases
    • Thompson AM, Fry DW, Kraker AJ and Denny WA (1994) Tyrosine kinase inhibitors. 2. Synthesis of 2,2′-dithiobis(1H-indole-3-alkanmides) and investigation of their inhibitory activity against epidermal growth factor receptor and pp60v-src protein tyrosine kinases. J Med Chem 37:598-608.
    • (1994) J Med Chem , vol.37 , pp. 598-608
    • Thompson, A.M.1    Fry, D.W.2    Kraker, A.J.3    Denny, W.A.4
  • 31
    • 0029556753 scopus 로고
    • Recent advances in protein tyrosine kinase inhibitors
    • Traxler P and Lydon N (1995) Recent advances in protein tyrosine kinase inhibitors. Drugs Future 20:1261-1274.
    • (1995) Drugs Future , vol.20 , pp. 1261-1274
    • Traxler, P.1    Lydon, N.2
  • 32
    • 0028263055 scopus 로고
    • Dianilinopthalimides: Potent and selective, ATP competitive inhibitors of the EGF-receptor protein tyrosine kinase
    • Trinks U, Buchdunger E and Furet P (1994) Dianilinopthalimides: potent and selective, ATP competitive inhibitors of the EGF-receptor protein tyrosine kinase. J Med Chem 37:1015-1027.
    • (1994) J Med Chem , vol.37 , pp. 1015-1027
    • Trinks, U.1    Buchdunger, E.2    Furet, P.3
  • 33
    • 0025343230 scopus 로고
    • Signal transduction by receptors with tyrosine kinase activity
    • Ullrich A and Schlessinger J (1990) Signal transduction by receptors with tyrosine kinase activity. Cell 61:203-212.
    • (1990) Cell , vol.61 , pp. 203-212
    • Ullrich, A.1    Schlessinger, J.2
  • 34
    • 0027762048 scopus 로고
    • Angiogenic role of endogenous basic fibroblast growth factor released by rat aorta after injury
    • Villaschi S and Nicosia RF (1993) Angiogenic role of endogenous basic fibroblast growth factor released by rat aorta after injury. Am J Pathol 143:181-190.
    • (1993) Am J Pathol , vol.143 , pp. 181-190
    • Villaschi, S.1    Nicosia, R.F.2
  • 35
    • 0028106163 scopus 로고
    • Epidermal growth factor receptor tyrosine kinase: Investigation of catalytic mechanism, structure-based searching and discovery of a potent inhibitor
    • Ward WHJ, Cook PN, Slater AM, Davies H, Holdgate GA and Green LR (1994) Epidermal growth factor receptor tyrosine kinase: Investigation of catalytic mechanism, structure-based searching and discovery of a potent inhibitor. Biochem Pharmacol 48:659-666.
    • (1994) Biochem Pharmacol , vol.48 , pp. 659-666
    • Ward, W.H.J.1    Cook, P.N.2    Slater, A.M.3    Davies, H.4    Holdgate, G.A.5    Green, L.R.6
  • 36
    • 0029951570 scopus 로고    scopus 로고
    • Phenylamino-pyrimidine (PAP)-derivatives: A new class of potent and highly selective PDGF-receptor autophosphorylation inhibitors
    • Zimmermann J, Buchdunger E, Mett H, Meyer T, Lydon NB and Traxler P (1996) Phenylamino-pyrimidine (PAP)-derivatives: A new class of potent and highly selective PDGF-receptor autophosphorylation inhibitors. Bioorg Med Chem Lett 6:1221-1226.
    • (1996) Bioorg Med Chem Lett , vol.6 , pp. 1221-1226
    • Zimmermann, J.1    Buchdunger, E.2    Mett, H.3    Meyer, T.4    Lydon, N.B.5    Traxler, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.