A Mutation in the Gene-encoding Bacteriophage T7 DNA Polymerase That Renders the Phage Temperature-sensitive

Journal of Biological Chemistry

Volumn 276, Issue 49, 2001, Pages 46151-46159

  Kumar, Jaya K ^b   Kremsdorf, Robin ^b   Tabor, Stanley ^b   Richardson, Charles C ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIOASSAY; CELLS; DNA; ENZYMES; SYNTHESIS (CHEMICAL);

EXONUCLEASE DOMAIN;

GENES;

ALANINE; CELL EXTRACT; DNA POLYMERASE; SOLUBLE GENE 5 PROTEIN; UNCLASSIFIED DRUG; VALINE; VIRUS PROTEIN; BACTERIOPHAGE T7 INDUCED DNA POLYMERASE; DNA DIRECTED DNA POLYMERASE; PRIMER DNA;

AMINO ACID SUBSTITUTION; ARTICLE; BACTERIOPHAGE T7; DNA SYNTHESIS; ENZYME ACTIVITY; ENZYME INDUCTION; ESCHERICHIA COLI; EXONUCLEASE DOMAIN; GENE MUTATION; NONHUMAN; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN MISFOLDING; TEMPERATURE SENSITIVE MUTANT; TEMPERATURE SENSITIVITY; VIRUS GENE; VIRUS INACTIVATION; VIRUS INFECTION; VIRUS REPLICATION; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; DNA REPLICATION; GENETICS; HEAT; MUTAGENESIS; NUCLEOTIDE SEQUENCE; PROTEIN CONFORMATION; VIROLOGY;

ESCHERICHIA COLI;

BASE SEQUENCE; DNA PRIMERS; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; ESCHERICHIA COLI; GENES, VIRAL; HEAT; MODELS, MOLECULAR; MUTAGENESIS; PROTEIN CONFORMATION; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; VIRAL PROTEINS;

EID: 0035824691     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M106319200     Document Type: Article

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