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Volumn 276, Issue 5310, 1997, Pages 227-232

Phylogenetic methods come of age: Testing hypotheses in an evolutionary context

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOGENESIS; COMPUTER SIMULATION; DNA SEQUENCE; HOST PARASITE INTERACTION; PHYLOGENY; PRIORITY JOURNAL;

EID: 0030902563     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.276.5310.227     Document Type: Article
Times cited : (667)

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    • note
    • The LRT statistic for the test of congruence was calculated assuming a F81 (70) model of DNA substitution. This model allows for different equilibrium nucleotide frequencies but assumes that the rate of transitions is equal to the rate of transversions. The significance of the LRT statistic -2 log A = 69.58 was approximated using the parametric bootstrap procedure.
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    • note
    • We thank J. Bull, J. Garza, D. Hillis, R. Nielsen, A. Meyer, M. Slatkin, D. Wake, T. Wiehe, and Z. Yang for critical review of the manuscript. Supported by NIH grant GM40282 to M. Slatkin, a Miller postdoctoral fellowship (J.H.), and a Natural Sciences and Engineering Research Council (NSERC) of Canada postdoctoral fellowship (B.R.).


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