Structure, histone deacetylase, and antiprotozoal activities of apicidins B and C, congeners of apicidin with proline and valine substitutions

Organic Letters

Volumn 3, Issue 18, 2001, Pages 2815-2818

  Singh, Sheo B ^a   Zink, Deborah L ^a   Liesch, Jerrold M ^a   Dombrowski, Anne W ^a   Darkin Rattray, Sandra J ^a   Schmatz, Dennis M ^a   Goetz, Michael A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPROTOZOAL AGENT; APICIDIN; CYCLOPEPTIDE; HISTONE DEACETYLASE; PROLINE; VALINE;

AMINO ACID SUBSTITUTION; ANIMAL; ARTICLE; CHEMISTRY; COCCIDIA; CONFORMATION; DRUG ANTAGONISM; DRUG EFFECT; DRUG SENSITIVITY; EIMERIA TENELLA; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

AMINO ACID SUBSTITUTION; ANIMALS; ANTIPROTOZOAL AGENTS; EIMERIA TENELLA; HISTONE DEACETYLASES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; PARASITIC SENSITIVITY TESTS; PEPTIDES, CYCLIC; PROLINE; SARCOCYSTIDAE; VALINE;

EID: 0035817996     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol016240g     Document Type: Article

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