Synthesis of N-alkyl substituted indolocarbazoles as potent inhibitors of human cytomegalovirus replication

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 15, 2001, Pages 1993-1995

  Slater, Martin J ^a   Baxter, Robert ^a   Bonser, Robert W ^a   Cockerill, Stuart ^a   Gohil, Kam ^a   Parry, Nigel ^a   Robinson, E ^a   Randall, Roger ^a   Yeates, Clive ^a   Snowden, Wendy ^a   Walters, Adeline ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

12 ETHYL 12,13 DIHYDRO 5H INDOLO[3,4 C]CARBAZOLE 5,7(6H) DIONE; ALKYL GROUP; ANTIVIRUS AGENT; ARCYRIAFLAVIN A; GANCICLOVIR; INDOLE DERIVATIVE; INDOLECARBAZOLE DERIVATIVE; NITROGEN; UNCLASSIFIED DRUG;

ALKYLATION; ANIMAL CELL; ANTIBIOTIC RESISTANCE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; INFLUENZA VIRUS A; NONHUMAN; STRUCTURE ACTIVITY RELATION; VARICELLA ZOSTER VIRUS; VIRUS INHIBITION; VIRUS ISOLATION; VIRUS REPLICATION;

ANTIVIRAL AGENTS; CARBAZOLES; CELLS, CULTURED; CYTOMEGALOVIRUS; DRUG RESISTANCE; GANCICLOVIR; HUMANS; INDOLES; INHIBITORY CONCENTRATION 50; PROTEIN KINASE C; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS REPLICATION;

HUMAN HERPESVIRUS 5;

EID: 0035817257     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00352-3     Document Type: Article

References (24)