Synthesis and anti-herpes virus activity of 2′-deoxy-4′-thiopyrimidine nucleosides

Journal of Medicinal Chemistry

Volumn 39, Issue 3, 1996, Pages 789-795

  Rahim, S George ^a   Trivedi, Naimisha ^a   Bogunovic Batchelor, Mirjana V ^a   Hardy, George W ^a   Mills, Gail ^a   Selway, John W T ^a   Snowden, Wendy ^a   Littler, Edward ^a   Coe, Paul L ^b   Basnak, Ivan ^b   Whale, Robert F ^b   Walker, Richard T ^b  

^a WELLCOME RESEARCH LABORATORIES   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2' DEOXY 4' THIO 5 VINYLURIDINE; 2' DEOXY 5 ETHYL 4' THIOURIDINE; 2' DEOXY 5 ISOPROPYL 4' THIOURIDINE; 2' DEOXY 5 PROPYL 4' THIOURIDINE; 5 (2 CHLOROETHYL) 2' DEOXY 4' THIOURIDINE; 5 CYCLOPROPYL 2' DEOXY 4' THIOURIDINE; ANTIVIRUS AGENT; NUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HERPES VIRUS; HUMAN; HUMAN CELL; VARICELLA ZOSTER VIRUS; VIRUS INHIBITION;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; HUMANS; PLAQUE ASSAY; PYRIMIDINE NUCLEOSIDES; SIMPLEXVIRUS; VERO CELLS;

EID: 0030058150     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950029r     Document Type: Article

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