Identification and characterization of a Plasmodium falciparum RNA polymerase gene with similarity to mitochondrial RNA polymerases

Molecular and Biochemical Parasitology

Volumn 113, Issue 2, 2001, Pages 261-269

  Li, Jiangning ^a   Maga, John A ^a,b   Cermakian, Nicolas ^c,d   Cedergren, Robert ^c   Feagin, Jean E ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Apicomplexa; Malaria; Mitochondria; Plasmodium falciparum; Plastid; RNA polymerase

Indexed keywords

AMINO ACID; ISOENZYME; MITOCHONDRIAL ENZYME; RNA POLYMERASE;

AMINO ACID ANALYSIS; AMINO TERMINAL SEQUENCE; ANALYTIC METHOD; ARTICLE; CELL ORGANELLE; DNA FLANKING REGION; GENE AMPLIFICATION; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; RNA SEQUENCE; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DNA-DIRECTED RNA POLYMERASES; GENES, PROTOZOAN; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; VIRAL PROTEINS;

ANIMALIA; APICOMPLEXA; PLASMODIUM FALCIPARUM; T7 PHAGE;

EID: 0035815328     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(01)00223-7     Document Type: Article

References (44)

1. Oxygen- and time-dependent effects of antibiotics and selected mitochondrial inhibitors on Plasmodium falciparum in culture
2. Effects of mitochondrial inhibitors on intraerythrocytic Plasmodium falciparum in in vitro cultures
3. Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparum
4. Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs
5. Mitochondrial genome diversity in parasites
6. Complete gene map of the plastid-like DNA of the malaria parasite Plasmodium falciparum
7. Inhibition of Plasmodium falciparum protein synthesis: Targeting the plastid-like organelle with thiostrepton
8. The 6 kb element of Plasmodium falciparum is polycistronically transcribed
9. The fragmented mitochondrial ribosomal RNAs of Plasmodium falciparum have short A tails
10. Transcriptional mapping and RNA processing of the Plasmodium falciparum mitochondrial genome
11. Plasmodium falciparum: Alterations in organelle transcript abundance during the erythrocytic cycle
12. Bacterial orthologues indicate the malarial plastid gene ycf24 is essential
13. Yeast mitochondrial RNA polymerase is homologous to those encoded by bacteriophages T3 and T7
14. Cloning and characterization of the Neurospora crassa cyt-5 gene
15. The genome sequence of Drosophila melanogaster
16. Identification of the gene encoding the human mitochondrial RNA polymerase (h-mtRPOL) by cyberscreening of the expressed sequence Tag database
17. Identification and characterization of T3/T7 bacteriophage-like RNA polymerase sequences in wheat
18. Characterization of a gene encoding a single-subunit bacteriophage-type RNA polymerase from maize which is alternatively spliced
19. Functional analysis of two maize cDNAs encoding T7-like RNA polymerases
20. Cloning and characterization of a cDNA encoding a bacteriophage-type RNA polymerase from the higher plant Chenopodium album
21. Mitochondrial and chloroplast phage-type RNA polymerases in Arabidopsis
22. Organellar RNA polymerases of higher plants
23. Sequences homologous to yeast mitochondrial and bacteriophage T3 and T7 RNA polymerases are widespread throughout the eukaryotic lineage
24. Evidence for two RNA polymerase activities in Euglena gracilis chloroplasts
25. Disruption of rpoB reveals a second distinct transcription system in plastids of higher plants
26. S-antigens and isozymes in strains of Plasmodium falciparum
27. Cultivation of malarial parasites
28. Organization and expression of small subunit ribosomal RNA genes encoded by a 35-kb circular DNA in Plasmodium falciparum
29. A procedure for in vitro amplification of DNA segments that lie outside the boundaries of known sequences
30. Structural and mechanistic relationships between nucleic acid polymerases
31. Asp537 and Asp812 in bacteriophage T7 RNA polymerase as metal-ion binding sites studied by EPR, flow dialysis, and transcription
32. Asp537, Asp812 are essential and Lys631,His811 are catalytically significant in bacteriophage T7 RNA polymerase activity
33. Mutations in T7 RNA polymerase that support the proposal for a common polymerase active site structure
34. Isolation and characterization of mutant bacteriophage T7 RNA polymerases
35. A mutant T7 RNA polymerase as a DNA polymerase
36. Mutants of T7 RNA polymerase that are able to synthesize both RNA and DNA
37. On the evolution of the single-subunit RNA polymerases
38. Crystal structure of bacteriophage T7 RNA polymerase at 3.3 Å resolution
39. Protein trafficking to the plastid of Plasmodium falciparum is via the secretory pathway
40. Analysis of targeting sequences demonstrates that trafficking to the Toxoplasma gondii plastid branches off the secretory system
41. Transcription in chloroplasts and mitochondria: A tale of two polymerases
42. The structure and role of RNA polymerases in Plasmodium
43. The gene encoding DNA polymerase α from Plasmodium falciparum
44. A family of cation ATPase-like molecules from Plasmodium falciparum