Regulation of serotonin transporter gene expression in human glial cells by growth factors

European Journal of Pharmacology

Volumn 417, Issue 1-2, 2001, Pages 69-76

  Kubota, Nobuo ^a   Kiuchi, Yuji ^a   Nemoto, Mariko ^a   Oyamada, Hideto ^a   Ohno, Minoru ^a   Funahashi, Hisayuki ^a   Shioda, Seiji ^a   Oguchi, Katsuji ^a  

^a SHOWA UNIVERSITY   (Japan)

Author keywords

5 HT (5 hydroxytryptamine, serotonin) transporter; 5 HT (5 hydroxytryptamine, serotonin) uptake; Basic fibroblast growth factor; Epidermal growth factor (human); Glia

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; COMPLEMENTARY DNA; DOPAMINE TRANSPORTER; EPIDERMAL GROWTH FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; GROWTH FACTOR; MESSENGER RNA; NORADRENALIN TRANSPORTER; SEROTONIN TRANSPORTER;

ARTICLE; ASTROCYTE; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GLIA CELL; GLIOMA; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEROTONIN UPTAKE;

ASTROCYTES; CARRIER PROTEINS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION; GLIOMA; GROWTH SUBSTANCES; HUMANS; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; NEUROGLIA; RNA, MESSENGER; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0035815270     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)00906-2     Document Type: Article

References (29)

1. Antidepressant drugs inhibit a glial 5-hydroxytryptamine transporter in rat brain
2. Na(+)-dependent, fluoxetine-sensitive serotonin uptake by astrocytes tissue-printed from rat cerebral cortex
3. Basic fibroblast growth factor (bFGF) injection activates the glial reaction in the injured adult rat brain
4. Glial cell line-derived neurotrophic factor protects dopaminergic neurons from 6-hydroxydopamine toxicity in vitro
5. Increased basic fibroblast growth factor (bFGF) immunoreactivity at the site of focal brain wounds
6. Ischemia-induced extracellular release of serotonin plays a role in CA1 neuronal cell death in rats
7. Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter
8. Astroglia in CNS injury
9. Growth factors and gangliosides as neuroprotective agents in excitotoxicity and ischemia
10. 3H]5-HT uptake into glial plasmalemmal vesicles
11. Cloning of a serotonin transporter affected by antidepressants
12. Pharmacological characterization of dopamine transport in cultured rat astrocytes
13. Regulation of dopamine uptake by basic fibroblast growth factor and epidermal growth factor in cultured rat astrocytes
14. Serotonin may have neurotoxic properties
15. Kinetics and autoradiography of high affinity uptake of serotonin by primary astrocyte cultures
16. Human serotonin transporter: Regulation by the neuroprotective agent aurintricarboxylic acid and by epidermal growth factor
17. Ketanserin reduces neuronal calcium accumulation and cell death in the hippocampus of the Mongolian gerbil after transient forebrain ischemia
18. Reverse transcriptase-polymerase chain reaction (RT-PCR) analysis of monoamine transporters in neuroblastoma cell lines: Correlations to meta-iodobenzylguanidine (MIBG) uptake and tyrosine hydroxylase gene expression
19. Ischemic neuronal injury is ameliorated by astrocyte activation
20. Role of hippocampal serotonergic neurons in ischemic neuronal death
21. Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter
22. Traumatic brain injury leads to increased expression of peripheral-type benzodiazepine receptors, neuronal death, and activation of astrocytes and microglia in rat thalamus
23. Antidepressant- and cocaine-sensitive human serotonin transporter: Molecular cloning, expression, and chromosomal localization
24. 14C-5-hydroxytryptamine in slices and srude synaptosome preparations of the midbrain-hypothalamus region of the rat brain
25. DNA sequencing with chain-terminating inhibitors
26. Cloning and expression of a cocaine-sensitive dopamine transporter complementary DNA
27. Expression of the extraneuronal monoamine transporter (uptake2) in human glioma cells
28. Upregulation of fibroblast growth factor-receptor messenger RNA expression in rat brain following transient forebrain ischemia
29. Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain