A novel permissive role for glucocorticoids in induction of febrile and behavioral signs of experimental herpes simplex virus encephalitis

Neuroscience

Volumn 108, Issue 1, 2001, Pages 119-127

  Ben Hur, T ^a   Cialic, R ^a   Itzik, A ^a   Barak, O ^b   Yirmiya, R ^b   Weidenfeld, J ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Adrenocortical axis; Fever; Interleukin 1; Motor activity; Prostaglandin E2; Viral encephalitis

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; INTERLEUKIN 1BETA; MESSENGER RNA; PROSTAGLANDIN E2;

ADRENALECTOMY; AGGRESSION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BEHAVIOR DISORDER; BRAIN SLICE; CELL CULTURE; CONTROLLED STUDY; FEVER; GENE EXPRESSION; HERPES SIMPLEX ENCEPHALITIS; HERPES SIMPLEX VIRUS 1; HORMONE SUBSTITUTION; HYPERACTIVITY; HYPOPHYSECTOMY; MALE; MORTALITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; RAT; RECEPTOR BLOCKING;

ADRENALECTOMY; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; DINOPROSTONE; ENCEPHALITIS, HERPES SIMPLEX; FEVER; GENE EXPRESSION; GLUCOCORTICOIDS; HERPESVIRUS 1, HUMAN; HYPOPHYSECTOMY; INTERLEUKIN-1; MALE; RATS; RECEPTORS, GLUCOCORTICOID;

EID: 0035814446     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(01)00404-3     Document Type: Article

References (34)

1. Two neurotropic viruses, herpes simplex virus type 1 and mouse hepatitis virus, spread along different neural pathways from the main olfactory bulb
2. Adrenocortical activation by herpes virus: Involvement of IL-1 beta and central noradrenergic system
3. HSV-1 virulence for mice by the intracerebral route is encoded by the BamHI-L DNA fragment containing the cell fusion gene
4. Effects of HSV-1, a neurotropic virus, on the hypothalamic-pituitary-adrenocortical axis in rats
5. Neurovirulence of herpes simplex virus type 1 depends on age in mice and thymidine kinase expression
6. Growth and fate of PSA-NCAM+ precursors of the postnatal brain
7. Rescue of HSV-1 neurovirulence is associated with induction of brain interleukin-1 expression, prostaglandin synthesis and neuroendocrine responses
8. HSV-1 DNA sequence determining intraperitoneal pathogenicity in mice is required for transcription of viral immediate-early genes in macrophages
9. Cytokines and fever
10. Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture
11. Prostaglandin E2 in the pathogenesis of fever. An update
12. Molecular basis of sickness behavior
13. Cytokines as endogenous pyrogens
14. Cross-talk between steroids and NF-kappa B: What language?
15. Adrenalectomy enhances pro-inflammatory cytokines gene expression, in the spleen, pituitary and brain of mice in response to lipopolysaccharide
16. Mechanisms of herpes simplex virus type 1 reactivation
17. Differential effects of nerve growth factor and dexamethasone on herpes simplex virus type 1 oriL- and oriS-dependent DNA replication in PC12 cells
18. Molecular and biological characterization of a herpes simplex virus type 1 (HSV-1) neuroinvasiveness gene
19. Interleukin-1 induces changes in norepinephrine metabolism in the rat brain
20. Cytokines and fever
21. Selective lesions of neural pathways following viral inoculation of the olfactory bulb
22. Glucocorticoids and stress: Permissive and suppressive actions
23. Role of the hypothalamic pituitary adrenal axis and IL-6 in stress-induced reactivation of latent herpes simplex virus type 1
24. Brain monoamine metabolism and rotational behaviour induced by experimental herpes simplex virus encephalitis
25. Corticosterone controls interleukin-1 beta expression and sickness behavior in the rat
26. The neurologic basis of fever
27. Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors
28. Prostaglandin E as the neural mediator of the febrile response
29. Effect of interleukin-1 on ACTH and corticosterone secretion in dexamethasone and adrenalectomized pretreated male rats
30. Effect of bacterial endotoxin and interleukin-1 on prostaglandin biosynthesis by the hippocampus of mouse brain: Role of interleukin-1 receptors and glucocorticoids
31. Effects of adrenalectomy and corticosterone replacement on the hypothalamic-pituitary response to neural stimuli
32. Cytokines, 'depression due to a general medical condition, ' and antidepressant drugs
33. A negative regulatory region containing a glucocorticosteroid response element (nGRE) in the human interleukin-1beta gene