Rescue of HSV-1 neurovirulence is associated with induction of brain interleukin-1 expression, prostaglandin synthesis and neuroendocrine responses

Journal of NeuroVirology

Volumn 2, Issue 4, 1996, Pages 279-288

  Ben Hur, Tamir ^a   Rosenthal, Jutta ^a   Itzik, Anna ^a   Weidenfeld, Joseph ^a  

^a HEBREW UNIVERSITY   (Israel)

Author keywords

Adrenocortical axis; HSV 1; Interleukin 1; Neurovirulence; Prostaglandins; U(L)53 gene

Indexed keywords

BRAIN PROTEIN; INTERLEUKIN 1; INTERLEUKIN 1BETA; MESSENGER RNA; PROSTAGLANDIN; PROSTAGLANDIN E2; VIRUS DNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; DEATH; DISEASE COURSE; ENCEPHALITIS; GENE EXPRESSION; GENE INDUCTION; GENE MAPPING; GENE TRANSFER; HERPES SIMPLEX VIRUS 1; HERPES VIRUS INFECTION; HORMONE BLOOD LEVEL; HORMONE RELEASE; HYPOTHALAMUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RAT; THALAMUS MIDLINE NUCLEUS; VIRUS GENOME; VIRUS REPLICATION; VIRUS VIRULENCE;

ANIMALIA; DNA VIRUSES; HERPES; HERPESVIRIDAE; HUMAN HERPESVIRUS 1;

EID: 0029815811     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.3109/13550289609146891     Document Type: Article

References (45)

1. Antoni FA (1986). Hypothalamic control of adrenocorticotropin secretion: advances since the discovery of 41-residue corticotropin-releasing factor. Endocrine Rev 7: 351-378.
2. Ban E, Haour F, Lenstra R (1992). Brain interleukin 1 gene expression induced by peripheral lipopolysaccharide administration. Cytokine 4: 48-54.
3. Becker Y, Hadar J, Tabor E, Ben-Hur T, Raibstein I, Rosen A, Darai G (1986). A sequence in Hpal-P fragment of herpes simplex virus-1 DNA determines intraperitoneal virulence in mice. Virology 149: 255-259.
4. Ben-Hur T, Hadar J, Shtram Y, Gilden DH, Becker Y (1983). Neurovirulence of herpes simplex virus type 1 depends on age in mice and thymidine kinase expression. Arch Virol 78: 303-308.
5. Ben-Hur T, Asher Y, Tabor E, Darai G, Becker Y (1987). HSV-1 virulence for mice by the intracerebral route is encoded by the BamHI-L DNA fragment containing the cell fusion gene. Arch Virol 96: 117-122.
6. Ben-Hur T, Rosen-Wolff A, Lamade W, Darai G, Becker Y (1988). HSV-1 DNA sequence determining intraperitoneal pathogenicity in mice is required for transcription of viral immediate early genes in macrophages. Virology 163: 397-404.
7. Ben-Hur T, Conforti N, Itzik A, Weidenfeld J (1995). Effects of HSV-1, a neurotropic virus, on the hypothalamic-pituitary-adrenocortical axis in rats. Brain Res 702: 17-22.
8. Bond VC, Person S (1984). Fine structure physical map locations of alterations that affect cell fusion in herpes simplex virus type 1. Virology 132: 368-376.
9. Chirgwin JM, Pryzbyla AE, MacDonald RS, Rutter WS (1979). Isolation of biologically active ribonucleic acid from sources enriched in ribonucleases. Biochemistry 18: 5294-5299.
10. 134.5, a gene nonessential for growth in culture. Science 250: 1262-1266.
11. Dallman MF, Akana SF, Cascio CS, Darlington DN, Jacobson L, Levin N (1987). Regulation of ACTH secretion: Variation of a theme of B. Prog Horm Res 43: 113-173.
12. Day SP, Lausch RN, Oakes JE (1988). Evidence that the gene for the herpes simplex virus type 1 DNA polymerase accounts for the capacity of an intertypic recombinant to spread from eye to central nervous system. Virology 163: 166-173.
13. Field HJ, Coen DM (1986) Pathogenicity of herpes simplex virus mutants containing drug resistance mutations in the viral DNA polymerase gene. J Virol 60: 286-289.
14. Field HJ, Wildy P (1978). The pathogenicity of thymidine kinase - deficient mutants of herpes simplex virus in mice. J Hyg (Cambridge) 81: 267-277.
15. Fuller RW (1992). The involvement of serotonin in regulation of pituitary-adrenocortical function. Frontier in Neuroendocrinology 13: 250-270.
16. Giulian D, Corpuz M (1993). Microglial secretion products and their impact on the nervous system. Adv Neurol 59: 315-320.
17. Gordon Y, Gilden DH, Shtram Y, Asher Y, Tabor E, Wellish M, Devlin M, Snipper D, Hadar J, Becker Y (1983). A low thymidine kinase producing mutant of herpes simplex virus type 1 causes latent trigeminal ganglia infections in mice. Arch Virol 76: 39-49.
18. Hopkins SJ, Rothwell NJ (1995). Cytokines and the nervous system I: expression and regulation. Trends Neurosci 18: 83-88.
19. Hutchinson L, Goldsmith K, Snoddy D, Ghosh H, Graham FL, Johnson DC (1992). Identification and characterization of a novel herpes simplex glycoprotein, gK, involved in cell fusion. J Virol 66: 5603-5609.
20. Izumi KM, Stevens JG (1990). Molecular and biological characterization of a herpes simplex virus type 1 (HSV-1) neuroinvasiveness gene. J Exp Med 172: 487-496.
21. Javier RT, Izumi KM, Stevens JG (1988). Localization of a herpes simplex virus neurovirulence gene dissociated from high-titer virus replication in the brain. J Virol 62: 1381-1387.
22. Kapas L, Shibata M, Kimura M, Krueger JM (1994). Inhibition of nitric oxide synthesis suppresses sleep in rabbits. Am J Physiol 266: R151-R157.
23. Knudsen PS, Dinarello CA, Strom TB (1987). Glucocorticoids inhibit transcriptional and posttranscriptional expression of interleukin 1 in U937 cells. J Immunol 139: 4129-4134.
24. Lew W, Oppenheim JJ, Matsushima K (1988). Analysis of the suppression of IL-1α and IL-1β production in human peripheral blood mononuclear adherent cells by glucocorticoid hormone. J Immunol 140: 1895-1902.
25. Liebermann AP, Pitha PM, Shin HS, Shin ML (1989). Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus. Proc Natl Acad Sci USA 86: 6348-6352.
26. Meignier M, Longnecker R, Mavromara-Nazos P, Sears A, Roizman B (1988). Virulence of and establishment of latency by genetically engineered deletion mutants of herpes simplex virus 1. Virology 162: 251-254.
27. L53 gene of HSV-1 abolish virus neurovirulence to mice by the intracerebral route of injection. Virus Res 26: 99-112.
28. Pellegrino LJ, Pellegrino AS, Cushman AJA (1967). A stereotaxic atlas of the rat brain. Plenumk, New York, 1967.
29. Plotsky PM, Cunningham ET, Widmaier EP (1989). Catecholaminergic modulation of corticotropin-releasing factor and adrenocorticotropin secretion. Endocrine Rev 10: 437-458.
30. Pogue-Geile KL, Lee GT-Y, Shapira SK, Spear PG (1984). Fine mapping of mutations in the fusion-inducing MP strain of herpes simplex virus type 1. Virology 136: 100-109.
31. Roizman B, Kaplan LJ (1992). Herpes simplex viruses, central nervous system, and encephalitis: A two-body problem, with one outcome and too many questions, in: Raymond P. Roos (ed.), Molecular neurovirology, Humana press, Totowa, New Jersey, pp. 3-24.
32. Rosen A, Gelderblom H, Darai G (1985). Transduction of virulence in herpes simplex virus type 1 from a pathogenic to an apathogenic strain by a cloned viral DNA fragment. Med Microbiol Immunol 173: 257-278.
33. Rothwell NJ, Hopkins SJ (1995). Cytokines and the nervous system II: actions and mechanisms of action. Trends Neurosci 18: 130-136.
34. Rothwell NJ, Relton JK (1993). Involvement of cytokines in acute neurodegeneration in the CNS. Neurosci Biobehav Rev 17: 217-227.
35. Ruyechan WT, Morse LS, Knipe DM, Roizman B (1979). Molecular genetics of herpes simplex virus. H. Mapping of the major viral glycoproteins and of the genetic loci specifying the social behavior of infected cells. J Virol 29: 677-687.
36. Schobitz B, De Kloet ER, Holsboer F (1994). Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain. Prog Neurobiol 44: 397-432.
37. Thomas PS (1980). Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. Proc Natl Acad Sci USA 71: 5201-5205.
38. Thompson RL, Wagner EK, Stevens JG (1983). Physical location of a herpes simplex virus type 1 gene function(s) specifically associated with a 10 million fold increase in HSV neurovirulence. Virology 131: 180-192.
39. Thompson RL, Devi-Rao GV, Stevens JG, Wagner EK (1985). Rescue of a herpes simplex virus type 1 neurovirulence function with a cloned DNA fragment. J Virol 55: 504-508.
40. Waage A, Halstensen A, Shakaby R, Brandtxaeg P, Kierulf P, Espevik T (1989). Local production of tumor necrosis factor alpha, interleukin 1 and interleukin 6 in meningococcal meningitis. Relation to the inflammatory response. J Exp Med 170: 1859-1867.
41. Weidenfeld J, Rougeot C, Dray F, Feldman S (1989). Adrenocortical response following acute neurogenic stimuli is mediated by CRF-41. Neurosci Lett 107: 189-194.
42. Weidenfeld J, Kahbha K, Reches A, Shohami E (1992). Role of the central adrenergic system in the regulation of prostaglandin biosynthesis in rat brain. J Neurochem 58: 694-699.
43. Weidenfeld J, Feldman S (1993). Glucocorticoid feedback regulation of adrenocortical responses to neural stimuli: role of CRF-41 and corticosteroid type I and type II receptors. Neuroendocrinology 58: 49-56.
44. Whitnall MH (1993). Regulation of the hypothalamic corticotropin-releasing hormone neurosecretory system. Progress in Neurobiol 40: 573-629.
45. Yan HQ, Banos MA, Herregodts P, Hooghe R, Hooghe-Peters EL (1992). Expression of interleukin (IL)-1 beta, IL-6 and their respective receptors in the normal rat brain and after injury. Eur J Immunol 22: 2963-2971.