Escherichia coli PriA helicase: Fork binding orients the helicase to unwind the lagging strand side of arrested replication forks

Journal of Molecular Biology

Volumn 312, Issue 5, 2001, Pages 935-947

  Jones, Jessica M ^a   Nakai, Hiroshi ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Linkage of recombination and replication; PriA helicase; Replication restart; Replication fork arrest; Single strand binding protein

Indexed keywords

BACTERIAL ENZYME; HELICASE; PROTEIN PRIA; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYME SUBSTRATE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING;

ESCHERICHIA COLI;

EID: 0035812634     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4930     Document Type: Article

References (40)

1. An Escherichia coli replication protein that recognizes a unique sequence hairpin within a region of φX174 DNA
2. The ordered assembly of the φ174-type primosome: Isolation and identification of intermediate protein-DNA complexes
3. The ordered assembly of the φX174-type primosome: Preservation of primosome composition from assembly through replication
4. Unique primed start of phage phi X174 DNA replication and mobility of the primosome in a direction opposite chain elongation
5. The Escherichia coli primosome can translocate actively in either direction along the DNA strand
6. Escherichia coli replication factor Y, a component of the primosome, can act as a DNA helicase
7. The primosomal protein n′ of Escherichia coli is a DNA helicase
8. ATPase-deficient mutants of the Escherichia coli DNA replication protein PriA are capable of catalyzing the assembly of active primosomes
9. Inactivation of the Escherichia coli PriA DNA replication protein induces the SOS response
10. Replication deficiencies in priA mutants of Escherichia coli lacking the primosomal replication n′ protein
11. The DNA replication priming protein, PriA, is required for homologous recombination and double-strand break repair
12. A broadening view of recombinational DNA repair in bacteria
13. The importance of repairing stalled replication forks
14. PriA and T4 gp59: Factors that promote DNA replication on forked DNA substrates
15. Initiation of genetic recombination and recombination-dependent replication
16. Collapse and repair of replication forks in Escherichia coli
17. PriA-directed replication restart in Escherichia coli
18. DNA repair mechansisms
19. Analysis of DNA replication forks encountering a pyrimidine dimer in the template to the leading-strand
20. Differential replication of a single, UV-induced lesion in the leading or lagging-strand by a human cell extract: Fork uncoupling or gap formation
21. DNA double-strand breaks caused by replication arrest
22. Duplex opening by primosome protein PriA for replisome assembly on a recombination intermediate
23. PriA-directed assembly of a primosome on D loop DNA
24. Replication fork assembly at recombination intermediates is required for bacterial growth
25. The φX174-type primosome promotes replisome assembly at the site of recombination in bacteriophage Mu transposition
26. Interactions of Escherichia coli primary replicative helicase DnaB protein with single-stranded DNA. The nucleic acid does not wrap around the protein hexamer
27. The DNA replication protein PriA and the recombination protein RecG bind D-loops
28. Two modes of PriA binding to DNA
29. Kinetics of binding of single-stranded DNA binding protein from Escherichia coli to single-stranded nucleic acids
30. Assembly of the primosome of DNA replication in Escherichia coli
31. Differential ATP requirements distinguish the DNA translocation and DNA unwinding activities of the Escherichia coli PRI A protein
32. A prepriming DNA replication enzyme of Escherichia coli. II. Actions of protein n′: A sequence-specific, DNA-depdendent ATPase
33. Multiple pathways for restarting DNA replication forks in Escherichia coli K-12
34. Differential suppression of priA2::kan phenotypes in Escherichia coli K-12 by mutations in priA, lexA, and dnaC
35. Replisome assembly reveals the basis for asymmetric function in leading and lagging-strand replication
36. RecQ and RecJ process blocked replication forks prior to the resumption of replication in UV-irradiated Escherichia coli
37. Stable DNA replication: Interplay between DNA replication, homologous recombination, and transcription
38. How to measure and predict the molar absorption coefficient of a protein
39. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding