Effect of mass transfer limitations on the enzymatic kinetic resolution of epoxides in a two-liquid-phase system

Biotechnology and Bioengineering

Volumn 73, Issue 1, 2001, Pages 44-54

  Baldascini, Helen ^a   Ganzeveld, Klaassien J ^a   Janssen, Dick B ^a   Beenackers, Antonie A C M ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Epoxide hydrolase; Kinetic resolution; Lewis cell; Mass transfer, limitations; N octane; Two phase system

Indexed keywords

CELLS; STYRENE;

BIOCOMPATIBLE IMMISCIBLE SOLVENT;

PROTEINS;

EPOXIDE HYDROLASE; OCTANE;

ARTICLE; BIOCOMPATIBILITY; CATALYSIS; ENANTIOMER; ENZYME INACTIVATION; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME SUBSTRATE; EPOXIDATION; HYDROLYSIS; RHIZOBIUM RADIOBACTER; SOLUBILITY;

BIOREACTORS; ENZYME STABILITY; EPOXIDE HYDROLASES; EPOXY COMPOUNDS; HYDROLYSIS; KINETICS; MODELS, CHEMICAL; RHIZOBIUM; STEREOISOMERISM;

AGROBACTERIUM TUMEFACIENS; RADIOBACTER;

EID: 0035810303     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0290(20010405)73:1<44::AID-BIT1035>3.0.CO;2-C     Document Type: Article

References (33)

1. Epoxide hydrolases as asymmetric catalysts
2. Effect of interphase mixing on a water-organic solvent two-liquid phase microbial system: Ethanol fermentation
3. Effect of mass-transfer limitations on the selectivity of immobilized α-chymotrypsin biocatalysts prepared for use in organic medium
4. Chemical and biological synthesis of chiral epoxides
5. Integration of reaction and separation in manufacturing of pharmaceuticals: Membrane-mediated production of S-ibuprofen
6. Quantitative analyses of biochemical kinetic resolutions of enantiomers
7. Resolution of 1,2-epoxyhexane by Rhodotorula glutinis using a two-phase membrane bioreactor
8. Chirality in industry - An overview
9. Bioformation of optically pure epoxides
10. Biological routes to optically active epoxides
11. Inactivation of enzymes by organic solvents: New technique with well-defined interfacial area
12. Inactivation of alkene oxidation by epoxides in alkene- and alkane-grown bacteria
13. Rules for optimization of biocatalysis in organic solvents
14. Enantioselectivity of a recombinant epoxide hydrolase from Agrobacterium radiobacter
15. Multiphase membrane reactors for enzymatic resolution: Diffusional effects on stereoselectivity
16. Asymmetric hydrolysis of racemic para-nitrostyrene oxide using an epoxide hydrolase preparation from Aspergillus niger
17. Enantioselective hydrolysis of p-nitrostyrene oxide by an epoxide hydrolase preparation from Aspergillus niger
18. Microbiological transformations 32: Use of epoxide hydrolase mediated biohydrolysis as a way to enantiopure epoxides and vicinal diols: Application to substituted styrene oxide derivatives
19. Alkene monooxygenase-catalyzed whole cell epoxidation in a two-liquid phase system
20. Mass transfer and cholesterol oxidase kinetics in a liquid-liquid two-phase system
21. Kinetic mechanism of the enantioselective conversion of styrene oxide by epoxide hydrolase from Agrobacterium radiobacter AD1
22. Primary structure and catalytic mechanism of the epoxide hydrolase from Agrobacterium radiobacter AD1
23. The biotransformation of propylene to propylene oxide by methylococcus capsulatus (bath): 2. A study of the biocatalyst stability
24. Solid-to solid kinetic resolution. Determination of the enantiomeric ratio
25. Microbial transformation of epoxides
26. Asymmetric catalysis with water: Efficient kinetic resolution of terminal epoxides by means of catalytic hydrolysis
27. Stereochemistry in the oxidative metabolism of styrene by hepatic microsomes
28. Epoxide hydrolases from yeasts and other sources: Versatile tools in biocatalysis
29. Mechanistic studies of epoxide hydrolase utilizing a continuous spectrophotometric assay
30. Enantio- and regioselectivity in the epoxide-hydrolase-catalyzed ring opening of simple aliphatic oxiranes. Part I: Monoalkylsubstituted oxiranes
31. Understanding the influence of temperature change and cosolvent addition on conversion rate of enzymatic suspension reactions based on regime analysis