Investigation on the co-extrudability and spheronization properties of wet masses

International Journal of Pharmaceutics

Volumn 227, Issue 1-2, 2001, Pages 71-80

  Pinto, J F ^a   Lameiro, M H ^a   Martins, P ^a  

^a RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

Author keywords

Co extrusion; Extrusion; Pellets; Spheronization

Indexed keywords

DYE; LACTOSE; MICROCRYSTALLINE CELLULOSE; OIL SCARLET; WATER;

ARTICLE; DENSITY; DRUG FORMULATION; DRUG MANUFACTURE; ELECTRIC POTENTIAL; EVALUATION; FORCE; GEOMETRY; MOLECULAR SIZE; PELLET EXTRUSION; PRIORITY JOURNAL; RACEMIC MIXTURE; SPHERONIZATION; STEADY STATE; SURFACE PROPERTY; TECHNOLOGY; VELOCITY;

CELLULOSE; LACTOSE; PARTICLE SIZE; POWDERS; TECHNOLOGY, PHARMACEUTICAL;

EID: 0035807457     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(01)00786-4     Document Type: Article

References (12)

1. Study of formulation parameters on the physical-technique characteristics of theophylline granules obtained by extrusion-spheronization
2. Preparation of small solid pharmaceutical spheres
3. Bi-component extrusion of ceramic fibers
4. Convergent flow analysis in the extrusion of wet powder masses
5. Effects of surface-active agent on the size, shape and hardness of microcrystalline cellulose/maize starch pellets prepared by an extrusion-spheronization technique
6. Waxy corn starch: Potent cofiller in pellets produced by extrusion-spheronization
7. Screening study of lubricants in wet masses suitable for extrusion-spheronization
8. Influence of process variables on the preparation and properties of spherical granules by the process of extrusion and spheronization
9. A new technique for the production of spherical particles
10. Comparison between a twin-screw extruder and a rotary ring die press. Part 2. Influence of process variables
11. The influence of impeller design, method of screen perforation and perforation geometry on the quality of pellets made by extrusion-spheronization