Long-lasting induction of brain-derived neurotrophic factor is restricted to resistant cell populations in an animal model of status epilepticus

Neuroscience

Volumn 103, Issue 4, 2001, Pages 955-969

  Revuelta, M ^a   Castao, A ^a   Venero, J L ^a   Machado, A ^a   Cano, J ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

Apoptosis; BDNF; Cell death; Epilepsia; Gliosis; Kainate

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; KAINIC ACID; MESSENGER RNA;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL POPULATION; CONTROLLED STUDY; DISEASE MODEL; EPILEPTIC STATE; FEMALE; HIPPOCAMPUS; LIMBIC SYSTEM; MACROGLIA; MICROGLIA; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE;

ANIMALS; APOPTOSIS; BEHAVIOR, ANIMAL; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DEATH; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; EXCITATORY AMINO ACID AGONISTS; FEMALE; KAINIC ACID; NEUROGLIA; NEURONS; RATS; RATS, WISTAR; RNA, MESSENGER; STATUS EPILEPTICUS; TIME FACTORS;

EID: 0035804780     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(01)00032-X     Document Type: Article

References (71)

1. Glial fibrillary acidic protein in cryogenic lesions of the rat brain
2. Pathological finding in epilepsy
3. Hippocampal damage and kainic acid injection induce a rapid increase in RNA for BDNF and NGF in the rat brain
4. Astrocytes and microglial cells incorporate degenerating fibers following entorhinal lesion: A light confocal and electron microscopical study using a phagocytosis-dependent labeling technique
5. Identification of phagocytic glial cells after lesion-induced anterograde degeneration using double-fluorescence labeling: Combination of axonal tracing and lectin or immunostaining
6. Brain derived neurotrophic factor protects against ischemic cell damage in rat hippocampus
7. The role of epileptic activity in hippocampal and "remote" cerebral lesions induced by kainic acid
8. Electrographic, clinical and pathological alterations following systemic administration of kainic acid, bicuculline or pentrazole: Metabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy
9. Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures
10. Emergence and propagation of interictal spikes in the subcortically denervated hippocampus
11. Immediate early gene protein expression in neurons undergoing delayed death, but not necrosis, following hypoxic-ischaemic injury to the young rat brain
12. Regionally specific and rapid increases in BDNF mRNA in the adult rat brain following seizures induced by systemic administration of kainic acid
13. Differential regulation of catalytic and non-catalytic trkB messenger RNAs in the rat hippocampus following seizures induced by systemic administration of kainate
14. Immunohistochemical visualization of brain-derived neurotrophic factor in the rat brain
15. BDNF mRNA expression in the developing rat brain following kainic acid-induced seizure activity
16. Glial changes following an excitotoxic lesion in the CNS - II. Astrocytes
17. The distribution of the CR3 receptor on human cells and tissue as revealed by a monoclonal antibody
18. Glial fibrillary acidic protein (GFAP): The major protein of intermediate filaments in differentiated astrocytes
19. Increased levels of messenger RNAs for neurotrophic factors in the brain during kindling epileptogenesis
20. Microglial MHC antigen expression after ischemic and kainic acid lesions of the adult rat hippocampus
21. Brain-derived neurotrophic factor and neurotrophin-3 mRNAs are expressed in ventral midbrain regions containing dopaminergic neurons
22. Progression from ischemic injury to infarct following middle cerebral artery occlusion in the rat
23. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
24. Requirement for BDNF in activity-dependent survival of cortical neurons
25. The role of mononuclear phagocytes in wound healing after traumatic injury to adult mammalian brain
26. A permanent change in brain function resulting from daily electrical stimulation
27. BDNF and full length and truncated TrkB expression in the hippocampus of the rat following kainic acid excitotoxic damage. Evidence of complex time-dependent and cell-specific responses
28. Activity and injury-dependent expression of inducible transcription factors, growth factors and apoptosis-related genes within the central nervous system
29. BDNF is induced as an immediate early gene following NMDA receptor activation
30. BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: Temporal patterns of induction distinct from NGF
31. Microglial and astroglial reactions to ischemic and acid-induced lesions of the adult rat hippocampus
32. Aspartate, glutamate, and γ-aminobutyric acid depolarize cultured astrocytes
33. Seizure-induced differential expression of messenger RNAs for neurotrophins and their receptors in genetically fast and slow kindling rats
34. Induction of brain derived neurotrophic factor mRNA by seizures in neonatal and juvenile rat brain
35. Microglia: A sensor for pathological events in the CNS
36. Quantitative comparison of cell loss and thiopental-induced EEG changes in human epileptic hippocampus
37. Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 in the adult rat brain following cerebral ischemia and hypoglycemic coma
38. Neurotrophins and brain insults
39. The origin and nature of microglia
40. Epilepsy: A review of seizure types, etiologies, diagnosis, treatment and nursing complications
41. Kainic acid evokes a potassium efflux from astrocytes
42. Selective neuronal death in the contralateral hippocampus following unilateral kainate injections into the CA3 subfield
43. Glial changes following an excitotoxic lesion in the CNS - I. Microglia/macrophages
44. Kindling: An animal model of complex partial epilepsy
45. Cellular and molecular basis of epilepsy
46. Microglial and astrocytic cell response in the rat hippocampus after an intracerebroventricular kainic acid injection
47. Intrastriatal infusion of brain-derived neurotrophic factor: Retrograde transport and colocalisation with dopamine containing substantia nigra neurons in rat
48. Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells
49. 3H kainic acid after intraventricular injection
50. Development of functional complement receptors during in vitro maturation of human monocytes into macrophages
51. Glial reaction after seizure induced hippocampal lesion: Immunohistochemical characterization of proliferating cells
52. Macrophages and inflammation in the central nervous system
53. Widespread expression of BDNF but not NT-3 by target areas of basal forebrain cholinergic neurons
54. Kainate-induced apoptotic cell death in hippocampal neurons
55. Effects of kainic acid-induced seizures and ischemia on c-fos-like proteins in rat brain
56. Denervation-induced dendritic alterations in CA1 pyramidal cells following kainic acid hippocampal lesions in rats
57. Apoptosis and necrosis induced in different hippocampal neuron populations by repetitive perforant path stimulation in the rat
58. Functions of the neurotrophins during nervous system development: What the knockouts are teaching us
59. Kainic acid seizures in the rat
60. Neuronal activity up-regulates astroglial gene expression
61. Microglial activation by epileptic activities through the propagation pathway of kainic acid-induced hippocampal seizures in the rat
62. Brain macrophages: Evaluation of microglia and their functions
63. Regionally specific induction of BDNF and truncated trkB. T1 receptors in the hippocampal formation after intraseptal injection of kainic acid
64. Delayed apoptotic pyramidal cell death in CA4 and CA1 hippocampal subfields after a single intraseptal injection of kainate
65. Neuronal death and survival in two models of hypoxic-ischemic brain damage
66. Pathophysiological mechanism of brain damage from status epilepticus
67. Brain-derived neurotrophic factor: Subcellular compartmentalization and interneuronal transfer as visualized with anti-peptide antibodies
68. Activation of glutamate receptors and glutamate uptake in identified microglial cells in rat cerebellar cultures
69. Local and distant neuronal degeneration following intrastriatal injection of kainic acid
70. Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors