Crystal structure of glutamate-1-semialdehyde aminomutase: An α2-dimeric vitamin B6-dependent enzyme with asymmetry in structure and active site reactivity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 10, 1997, Pages 4866-4871

  Hennig, Michael ^a,d   Grimm, Bernhard ^b   Contestabile, Roberto ^c   John, Robert A ^c   Jansonius, Johan N ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b LEIBNIZ INSTITUTE OF PLANT GENETICS AND CROP PLANT RESEARCH IPK   (Germany)

^c CARDIFF UNIVERSITY   (United Kingdom)

^d PRPS 65 308   (Switzerland)

Author keywords

Asymmetric dimer; Chlorophyll biosynthesis; Pyridoxal 5 phosphate; Reaction specificity; X ray structure analysis

Indexed keywords

ASPARTATE AMINOTRANSFERASE; GLUTAMATE 1 SEMIALDEHYDE AMINOMUTASE; PYRIDOXINE; UNCLASSIFIED DRUG;

ARTICLE; COVALENT BOND; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME STRUCTURE; PRIORITY JOURNAL; STEREOCHEMISTRY; THREE DIMENSIONAL IMAGING; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ARGININE; BINDING SITES; BOROHYDRIDES; CRYSTALLOGRAPHY, X-RAY; CYANOBACTERIA; CYCLOHEXANECARBOXYLIC ACIDS; DIMERIZATION; ESCHERICHIA COLI; GLUTAMIC ACID; INTRAMOLECULAR TRANSFERASES; ISOMERASES; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MODELS, STRUCTURAL; PROTEIN STRUCTURE, SECONDARY; PYRIDOXAL PHOSPHATE; RECOMBINANT PROTEINS; SCHIFF BASES; SUBSTRATE SPECIFICITY;

EID: 0030995422     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.10.4866     Document Type: Article

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