Eliciting the low-activity aldehyde dehydrogenase Asian phenotype by an antisense mechanism results in an aversion to ethanol

Journal of Experimental Medicine

Volumn 194, Issue 5, 2001, Pages 571-580

  Garver, E ^a   Tu, G C ^a   Cao, Q N ^a   Aini, M ^a   Zhou, F ^a   Israel, Y ^a,b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

Acetaldehyde; Alcoholism; ALDH2 2; Disulfiram; Treatment

Indexed keywords

ALCOHOL; ALDEHYDE DEHYDROGENASE; MESSENGER RNA; OLIGONUCLEOTIDE;

ALCOHOLISM; ANIMAL CELL; ARTICLE; ASIAN; AVERSION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; GENE EXPRESSION; GENE MUTATION; MALE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; RAT;

EID: 0035801331     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.194.5.571     Document Type: Article

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