Butyrate-induced differentiation of Caco-2 cells is mediated by vitamin D receptor

Biochemical and Biophysical Research Communications

Volumn 288, Issue 3, 2001, Pages 690-696

  Gaschott, Tanja ^a   Werz, Oliver ^a   Steinmeyer, Andreas ^b   Steinhilber, Dieter ^a   Stein, Jürgen ^a  

^a GOETHE UNIVERSITY   (Germany)

^b BAYER PHARMA AG   (Germany)

Author keywords

Butyrate; Caco 2 cells; Differentiation; P21Waf1 Cip1; Vitamin D receptor; Vitamin D receptor antagonist

Indexed keywords

BUTYRIC ACID; CALCITRIOL; PROTEIN P21; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR; VITAMIN D RECEPTOR ANTAGONIST; ZK 191732;

ARTICLE; CELL DIFFERENTIATION; CELL STRAIN CACO 2; COLON CANCER; DNA METHYLATION; DRUG EFFECT; DRUG RECEPTOR BINDING; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR UPREGULATION; TRANSCRIPTION REGULATION; TUMOR GROWTH;

EID: 0035798127     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.5832     Document Type: Article

References (34)

1. Rationale for the luminal provision of butyrate in intestinal diseases
2. Effect of short-chain fatty acids on the human colonic mucosa in vitro
3. Effect of structural analogues of propionate and butyrate on colon cancer cell growth
4. Butyrate-induced differentiation of Caco-2 cells occurs independently from p27
5. Role of short-chain fatty acids in the prevention of colorectal cancer
6. Hypomethylation of DNA during differentiation of Friend erythroleukemia cells
7. DNA hypermethylation in sodium butyrate-treated WI-38 fibroblasts
8. 3
9. 3) on neoplastic and osteoblastic phenotype in clonal rat osteosarcoma cells
10. 3 and sodium butyrate combination on differentiation and proliferation of HL-60 leukemia cells
11. Waf1/Cip1 expression
12. Tributyrin, a stable and rapidly absorbed prodrug of butyric acid, enhances antiproliferative effects of dihydroxycholecalciferol in human colon cancer cells
13. 3 and human bone derived-cells in vitro: Effects on alkaline phosphatase, type I collagen and proliferation
14. 3
15. Calcitriol and transforming growth factor-β upregulate 5-lipoxygenase mRNA expression by increasing gene transcription and mRNA maturation
16. Characterization of the vitamin D receptor from the Caco-2 human colon carcinoma cell line: Effect of cellular differentiation
17. 3
18. Vitamin D and regulation of gene expression
19. 3 receptor
20. WAF1 is required for butyrate-mediated growth inhibition of human colon cancer cells
21. Butyrate-induced differentiation of Caco-2 cells is associated with apoptosis and early induction of p21Waf1/Cip1 and p27Kip1
22. Short-chain fatty acids induce cell cycle inhibitors in colonocytes
23. Cell cycle arrest induced by the vitamin D(3) analog EB1089 in NCI-H929 myeloma cells is associated with induction of the cyclin-dependent kinase inhibitor p27
24. Effect of a novel vitamin D3 analog, EB1089, on G1 cell cycle regulatory proteins in HL-60 cells
25. Separation of lipoxins and leukotrienes from human granulocytes by high-performance liquid chromatography with a Radial-Pak cartridge after extraction with an octadecyl reversed-phase column
26. Selenium-dependent peroxidases suppress 5-lipoxygenase activity in B-lymphocytes and immature myeloid cells. The presence of peroxidase-insensitive 5-lipoxygenase activity in differentiated myeloid cells
27. 3 show cell-specific actions
28. 3
29. 3 receptor antagonists
30. 3 receptor-corepressor partnership
31. Ligand-triggered stabilization of vitamin D receptor/retinoid X receptor heterodimer conformations on DR4-type response elements
32. 3 is mediated by a lack of ligand-induced vitamin D receptor interaction with coactivators
33. Molecular basis of agonism and antagonism in the estrogen receptor
34. The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of human progesterone receptor