Regional expression of the splice variants of Kv4.3 in rat brain and effects of C-terminus deletion on expressed K+ currents

Life Sciences

Volumn 68, Issue 15, 2001, Pages 1703-1716

  Ohya, Susumu ^a   Tanaka, Mamiko ^a   Oku, Takuma ^a   Furuyama, Tatsuo ^b   Mori, Nozomu ^b   Giles, Wayne R ^c   Watanabe, Minoru ^a   Imaizumi, Yuji ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

^b NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^c UNIVERSITY OF CALGARY   (Canada)

Author keywords

A type K+ channel; C terminal deletion; Kv4.3 splice variant; Rat brain; RT PCR

Indexed keywords

MESSENGER RNA; POTASSIUM CHANNEL; POTASSIUM ION;

ALTERNATIVE RNA SPLICING; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CARBOXY TERMINAL SEQUENCE; CELL STRAIN; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; POTASSIUM CURRENT; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN ISOLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ANIMALS; BRAIN CHEMISTRY; GENE DELETION; IN SITU HYBRIDIZATION; MALE; MOLECULAR SEQUENCE DATA; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN ISOFORMS; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SHAL POTASSIUM CHANNELS;

STAPHYLOCOCCUS PHAGE 3A;

EID: 0035793839     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)00958-4     Document Type: Article

References (36)

1. Voltage-gated potassium channel genes
2. Identification of molecular components of A-type channels activating at sub-threshould potentials
3. + channels operating at subthreshould potentials with unique expression in heart and brain
4. Quantitative analysis of potassium channel mRNA expression in atrial and ventricular muscle of rats
5. + channel in ventricular muscle. A molecular correlate for the transient outward current
6. + current in rat ventricle
7. + current, by PKC
8. + channel splice variant common in human heart lacks a C-terminal domain required for expression of rapidly activating delayed rectifier current
9. + channel cloned from mammalian brain
10. + channel
11. + (A-type) currents in rat brain
12. + channel proteins in rat central neurons
13. to: Further diversity by alternative mRNA splicing
14. + channel α subunit, Kv4.3 in the rat
15. + channel subunit mRNAs in ventricles of renovascular hypertensive rats
16. + channel α subunit
17. + channel inactivation mediated by the concerted action of the cytoplasmic N- and C-terminal domains
18. Expression of copper trafficking genes in the mouse brain
19. Molecular cloning of a novel gene involved in serotonin receptor-mediated signal transduction in rat stomach
20. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
21. Characteristics of transient outward currents in single smooth muscle cells from the ureter of the guinea-pig
22. Effects of arachidonic acid on A-type potassium currents in smooth muscle cells of the guinea pig
23. Distinct spatial and temporal expression patterns of K1channel mRNAs from different subfamilies
24. + channel with unique localizations in mammalian brain: Molecular cloning and characterization
25. + channel mRNAs in the rat brain and down-regulation in the hippocampus following seizures
26. + channels rapidly alters activation and inactivation
27. out accelerates inactivation of Shal-channels responsible for A-current in rat CA1 neuron
28. + current diversity is produced by an extended gene family conserved in Drosophila and mouse
29. + channels
30. + channels
31. + channels by PSD-95
32. + channel Kv1.4
33. Clustering of Kv4.2 potassium channels in postsynaptic membrane of rat supraoptic neurons: An ultrastructural study
34. + channel
35. + currents in mammalian cell lines and cardiac myocytes