Increased expression but not genetic alteration of BRG1, a component of the SWI/SNF complex, is associated with the advanced stage of human gastric carcinomas

Pathobiology

Volumn 69, Issue 6, 2001, Pages 315-320

  Sentani, Kazuhiro ^a   Oue, Naohide ^a   Kondo, Humihiro ^a   Kuraoka, Kazuya ^a   Motoshita, Junichi ^a   Ito, Reiko ^a   Yokozaki, Hiroshi ^a   Yasui, Wataru ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

BRG1; Gastric carcinoma; Mutation

Indexed keywords

ONCOPROTEIN; PROTEIN BRG1; UNCLASSIFIED DRUG;

ADVANCED CANCER; ARTICLE; CANCER CELL CULTURE; CANCER STAGING; CANCER TISSUE; CONTROLLED STUDY; EXON; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; LYMPH NODE METASTASIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE STRAND CONFORMATION POLYMORPHISM; STOMACH CARCINOMA; STOMACH MUCOSA;

CARCINOMA; DISEASE PROGRESSION; DNA HELICASES; DNA MUTATIONAL ANALYSIS; DNA PRIMERS; DNA, NEOPLASM; GASTRIC MUCOSA; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MUTATION; NUCLEAR PROTEINS; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; STOMACH NEOPLASMS; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0035789816     PISSN: 10152008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000064638     Document Type: Article

References (33)

1. Yasui W, Yokozaki H, Fujimoto J, Naka K, Kuniyasu H, Tahara E: Genetic and epigenetic alterations in multistep carcinogenesis of the stomach. J Gastroenterol 2000;35:111-115.
2. Yasui W, Oue N, Kuniyasu H, Ito R, Tahara E, Yokozaki H: Molecular diagnosis of gastric cancer: Present and future. Gastric Cancer 2001;4:113-121.
3. Grunstein M: Histone acetylation in chromatin structure and transcription. Nature 1997;389:349-352.
4. Morales V, Richard-Foy H: Role of histone N-terminal tails and their acetylation in nucleosome dynamics. Mol Cell Biol 2000;20:7230-7237.
5. Ono S, Oue N, Kuniyasu H, Suzuki T, Ito R, Matsusaki K, Ishikawa T, Tahara E, Yasui W: Acetylated histone H4 is reduced in human gastric carcinomas. J Exp Clin Cancer Res, in press.
6. Wade PA, Wollfe AP: Transcriptional regulation: SWItching circuitry. Curr Biol 1999;9: 221-224.
7. Suzuki T, Yokozaki H, Kuniyasu H, Hayashi K, Naka K, Ono S, Ishikawa T, Tahara E, Yasui W: Effect of trichostatin A on cell growth and expression of cell cycle- and apoptosis-related molecules in human gastric and oral carcinoma cell lines. Int J Cancer 2000;88: 992-997.
8. Kingston RE, Narlikar GJ: ATP-dependent remodeling and acetylation as regulator of chromatin fluidity. Genes Dev 1999;13:2335-2352.
9. Phelan ML, Narlikar GJ, Kingston RE: Reconstitution of a core chromatin remodeling complexes from SWI/SNF subunits. Mol Cell 1999;3:247-253.
10. Tyler JK, Kadonaga JT: The 'dark side' of chromatin remodelling: Repressive effects on transcription. Cell 1999;99:443-446.
11. Zhang HS, Gavin M, Dahiya A, Postigo AA, Ma D, Luo RX, Harbour JW, Dean DC: Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF. Cell 2000;101:79-89.
12. Strobeck MW, Knudsen KE, Fribourg AF, De-Cristofaro MF, Weissman BE, Imbalzano AN, Knudsen ES: BRG-1 is required for RB-mediated cell cycle arrest. Proc Natl Acad Sci USA 2000;97:7748-7753.
13. Murphy DJ, Hardy SA, Engel DA: Human SWI-SNF component BRG1 represses transcription of the c-fos gene. Mol Cell Biol 1999; 19:2724-2733.
14. Bochar DA, Wang L, Beniya H, Kinev A, Xue Y, Lane WS, Wang W, Kashanchi F, Shiekhattar R: BRCA1 is associated with a human SWI/ SNF-related complex: Linking chromatin remodeling to breast cancer. Cell 2000;102:257-265.
15. Wong AKC, Shanahan F, Chen Y, Lian L, Ha P, Hendricks K, Ghaffari S, Iliev D, Penn B, Woodland A-M, Smith R, Salada G, Carillo A, Laity K, Gupte J, Swedlund B, Tavtigian SV, Teng DH-F, Lees E: BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines. Cancer Res 2000;60:6171-6177.
16. Yanagihara K, Seyama T, Tsumuraya M, Kamada N, Yokoro K: Establishment and characterization of human signet ring cell gastric carcinoma cell lines with amplification of the c-myconcogene. Cancer Res 1991;51:381-386.
17. Yokozaki H: Molecular characteristics of eight gastric cancer cell lines established in Japan. Pathol Int 2000;50:767-777.
18. Ochiai A, Yasui W, Tahara E: Growth-promoting effect of gastrin on human gastric carcinoma cell line TMK-1. Jpn J Cancer Res 1985;76:1064-1071.
19. Japanese Research Society for Gastric Cancer: Japanese Classification of Gastric Carcinoma, ed 1 (English). Tokyo, Kanehara, 1995.
20. Eads CA, Danenberg KD, Kawakami K, Saltz LB, Danenberg PV, Laird PW: CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression. Cancer Res 1999;59:2302-2306.
21. Burns LG, Peterson CL: The yeast SWI-SNF complex facilitates binding of a transcriptional activator to nucleosomal sites in vivo. Mol Cell Biol 1997;17:4811-4819.
22. Neely KE, Hassan AH, Wallberg AE, Steger DJ, Cairns BR, Wright APH, Workman JL: Activation domain-mediated targeting of the SWI/SNF complex to promoters stimulates transcription from nucleosome arrays. Mol Cell 1999;4:649-655.
23. Sudarsanam P, Cao Y, Wu L, Laurent BC, Winston F: The nucleosome remodeling com-plex, Snf/Swi, is required for the maintenance of transcription in vivo and is partially redun-dant with the histone acetyltransferase, Gcn5. EMBO J 1999;18:3101-3106.
24. Holstege FC, Jennings EG, Wyrick JJ, Lee TI, Hengartner CJ, Green MR, Golub TR, Lander ES, Young RA: Dissecting the regulatory circuitry of a eukaryotic genome. Cell 1998;95: 717-728.
25. Cheng SW, Davies KP, Yung E, Beltran RJ, Yu J, Kalpana GV: c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function. Nat Genet 1999;22:102-105.
26. Ito T, Yamauchi M, Nishina M, Yamamichi N, Mizutani T, Ui M, Murakami M, Iba H: Identification of SWI/SNF complex subunit BAF60a as a determinant of the transactivation potential of Fos/Jun dimers. J Biol Chem 2001;276:2852-2857.
27. Strobeck MW, DeCristofaro MF, Banine F, Weissman BE, Sherman LS, Knudsen ES: The BRG-1 subunit of the SWI/SNF complex regulates CD44 expression. J Biol Chem 2001;276:9273-9278.
28. Ue T, Yokozaki H, Yamamoto S, Yasui W, Ishikawa T, Tahara E: Co-expression of osteopontin and CD44v9 in gastric cancer. Int J Cancer 1998;79:127-132.
29. Yasui W, Kudo Y, Naka K, Fujimoto J, Ue T, Yokozaki H, Tahara E: Expression of CD44 containing variant exon 9 (CD44v9) in gastric adenomas and adenocarcinomas: Relation to the proliferation and progression. Int J Oncol 1998;12:1245-1251.
30. Trouche D, LeChalony C, Mucjardt C, Yaniv M, Kouzarides T: RB and hbrm cooperate to repress the activation functions of E2F1. Proc Natl Acad Sci USA 1997;94:11268-11273.
31. Wang W, Xue Y, Zhou S, Kuo A, Cairns BR, Crabtree GR: Diversity and specialization of mammalian SWI/SNF complexes. Genes Dev 1996;10:2117-2130.
32. Versteege I, Sevenet N, Lange J, Rousseau-Merck MF, Ambros P, Handgretinger R, Aurias A, Delattre O: Truncation mutations of hSNF5/INI1 in aggressive paediatric cancer. Nature 1998;394:203-206.
33. Grand F, Kulkarni S, Chase A, Goldman KM, Gordon M, Cross NCP: Frequent deletion of hSNF5/INI1, a component of the SWI/SNF complex, in chronic myeloid leukemia. Cancer Res 1999;59:3870-3874.