Pharmacophore model for antiepileptic drugs acting on sodium channels

Journal of Molecular Modeling

Volumn 7, Issue 7, 2001, Pages 231-239

  Tasso, Silvina M ^a   Bruno Blanch, Luis E ^a   Estiú, Guillermina L ^b,c  

^a FACULTAD DE CIENCIAS EXACTAS   (Argentina)

^b UNIVERSIDAD NACIONAL DE LA PLATA   (Argentina)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Antiepileptic; Pharmacophore; Quantum chemical molecular design; Rational drug design; Sodium channel

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; DEZINAMIDE; ETHOSUXIMIDE; FELBAMATE; GABAPENTIN; LAMOTRIGINE; OXCARBAZEPINE; PHENYTOIN; RALITOLINE; REMACEMIDE; RUFINAMIDE; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; TOPIRAMATE; VALPROIC ACID; VINPOCETINE; ZONISAMIDE;

ANTICONVULSANT ACTIVITY; ARTICLE; CHEMICAL INTERACTION; COMPUTER MODEL; CONFORMATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; ELECTRIC SHOCK; NERVE BLOCK; PHARMACOPHORE; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; QUANTUM CHEMISTRY; SEIZURE;

EID: 0035789704     PISSN: 16102940     EISSN: None     Source Type: Journal    
DOI: 10.1007/S008940100033     Document Type: Article

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