An intronic variant in PTEN is not associated with prostate cancer risk

Cancer Epidemiology Biomarkers and Prevention

Volumn 10, Issue 3, 2001, Pages 277-278

  Nathanson, Katherine L ^a   Omaruddin, Romaica ^a   Malkowicz, S Bruce ^a   Rebbeck, Timothy R ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

ADULT; ARTICLE; CANCER RISK; CONTROLLED STUDY; DISEASE ASSOCIATION; GENOTYPE; HETEROZYGOSITY LOSS; HUMAN; INTRON; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN VARIANT; RISK FACTOR;

AGE DISTRIBUTION; AGED; CASE-CONTROL STUDIES; COHORT STUDIES; HUMANS; MALE; MIDDLE AGED; MUTATION; ODDS RATIO; PHOSPHORIC MONOESTER HYDROLASES; POLYMORPHISM, GENETIC; PREVALENCE; PROGNOSIS; PROSTATIC NEOPLASMS; PTEN PHOSPHOHYDROLASE; REFERENCE VALUES; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS;

EID: 0035729651     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Mutational spectra of PTEN/MMAC1 gene: A tumor suppressor with lipid phosphatase activity
2. Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage
3. Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation
4. Pten is essential for embryonic development and tumor suppression
5. Polymorphisms in PTEN in breast cancer families
6. Re: "PTEN 1 is frequently mutated in primary endometrial carcinomas."
7. Infrequent genetic alterations of the PTEN/MMAC1 gene in Japanese patients with primary cancers of the breast, lung, pancreas, kidney, and ovary
8. Mutation and expression analysis of the putative prostate tumor-suppressor gene PTEN