Lipids stimulate the production of 6-keto-prostaglandin F1α in human dorsal hand veins

Hypertension

Volumn 38, Issue 4, 2001, Pages 858-863

  Haastrup, Adetola ^a   Gadegbeku, Crystal A ^a   Zhang, Da ^a   Mukhin, Yurii V ^a   Greene, Eddie L ^a   Jaffa, Ayad A ^a   Egan, Brent M ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Cyclooxygenase; Fatty acids; Muscle, vascular, smooth; Prostaglandins

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; FATTY ACID; HEPARIN; INDOMETACIN; LINOLEIC ACID; LIPID; MITOGEN ACTIVATED PROTEIN KINASE; OLEIC ACID; PHENYLEPHRINE; PHOSPHOLIPASE A2; PROSTACYCLIN; PROSTAGLANDIN F1 ALPHA; PROSTAGLANDIN H2; PROSTAGLANDIN SYNTHASE; PROTEIN KINASE C; THROMBOXANE A2; THROMBOXANE B2;

ADRENERGIC ACTIVITY; ADULT; ARTICLE; BLOOD VESSEL REACTIVITY; CALCIUM CELL LEVEL; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; HAND; HUMAN; HUMAN EXPERIMENT; HYPERTENSION; INSULIN RESISTANCE; MALE; NORMAL HUMAN; OBESITY; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; VASCULAR SMOOTH MUSCLE; VENOCONSTRICTION;

EID: 0035726275     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/hy1001.092615     Document Type: Article

References (36)

1. Mechanism of increased α-adrenergic vasoconstriction in human essential hypertension
2. Insulin resistant lipolysis in abdominally-obese hypertensives: Role of the renin-angiotensin system
3. Obesity hypertension is more closely related to impairment of insulin's fatty acid than glucose-lowering action
4. Fatty acids enhance vascular α-adrenergic sensitivity
5. 1-adrenergic receptor-mediated pressor sensitivity
6. Fatty acids augment endothelium-dependent dilation in hand veins by a cyclooxygenase-dependent mechanism
7. Reactive oxygen species are critical in the oleic-acid mediated mitogenic signaling pathway in vascular smooth muscle cells
8. 2+ and phospholipids
9. 2 is phosphorylated and activated by MAP kinase
10. Prostaglandin formation in man during intake of different amount of linoleic acid in formula diets
11. Reduction of blood pressure associated with dietary polyunsaturated fat
12. Additive effects of hypertension and obesity to limit venous distensibility
13. Rapid extraction of oxygenated metabolites of arachidonic acid from biological samples using octadecylsilyl silica
14. 2 by the aorta of spontaneously hypertensive rats
15. The smooth muscle cell in culture
16. FLIPR. A new instrument for accurate, high throughput optical screening
17. Identification of Gβγ-binding sites in the third intracellular loop of the M3-muscarinic receptor and their role in receptor regulation
18. Oleic acid and angiotensin induce a synergistic mitogenic response
19. 2 activities in canine vascular smooth muscle
20. Simultaneous measurement of cytosolic free calcium level and prostaglandin synthesis reveal a correlation between them in perfused monolayer of cultured rat vascular smooth muscle cells: Effects of bradykinin and angiotensin II
21. 1-adrenoceptors
22. 2-mediated mechanism of vascular contraction in hypertensive rats: Relation to lipoxygenase and prostacyclin synthase activities
23. Role of thromboxane in impaired renal vasodilation response to acetylcholine in hypercholesterolemic rats
24. Mechanism of decreased arachidonic acid in the renal cortex of rats with diabetes mellitus
25. 2+ and phospholipids
26. Oleic acid-induced mitogenic signaling in vascular smooth muscle cells: A role for protein kinase C
27. Direct regulation of ion channels by fatty acids
28. Assessment of the effect of drugs on the venous system in man
29. NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro
30. Cartilage cyvlic nucleotide phosphodiesterase: Inhibition by anti-inflammatory agents
31. Effects of indomethacin on fetal renal function, renal and umbilicoplacental blood flow and lung liquid production
32. Heparin-enhanced plasma phospholipase A2 activity and prostacyclin synthesis in patients undergoing cardiac surgery
33. Inhibitory effect of heparin cofactor II on thrombin-stimulated prostacyclin production by cultured vascular smooth muscle cells
34. Decreased prostacyclin production by human umbilical vein endothelial cells cultured with endothelial cell growth factor and heparin
35. Heparin and acidic fibroblast growth factor interact to decrease prostacyclin synthesis in human endothelial cells by affecting both prostaglandin H synthase and prostacyclin synthase