Oleic acid-induced mitogenic signaling in vascular smooth muscle cells: A role for protein kinase C

Circulation Research

Volumn 79, Issue 3, 1996, Pages 611-618

  Lu, Gang ^a   Morinelli, Thomas A ^a   Meier, Kathryn E ^a   Rosenzweig, Steven A ^a   Egan, Brent M ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

mitogenesis; oleic acid; protein kinase C; vascular remodeling; vascular smooth muscle cell

Indexed keywords

OLEIC ACID; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HYPERTENSION; LIPID ANALYSIS; MITOGENESIS; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

EID: 0029793916     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.res.79.3.611     Document Type: Article

References (52)

1. Stern M, Haffner S. Body fat distribution and hyperinsulinemia as risk factors for diabetes and cardiovascular diseases. Arteriosclerosis. 1986;6:123-129.
2. Gillum R. The association of body fat distribution with hypertension, hypertensive heart disease, CHD, diabetes and cardiovascular risk factors in men and women ages 18-79 years. J Chron Dis. 1987; 40:421-428.
3. Peiris A, Sothmann M, Hoffmann R, Hennes M, Wilson C, Gustafson A, Kissebah A. Adiposity, fat distribution and cardiovascular risk. Ann Intern Med. 1989;110:867-872.
4. Egan BM, Bassett DR, Block WD. Comparative effects of over-weight on cardiovascular risk in younger versus older men. Am J Cardiol. 1991;67:248-252.
5. Reaven GM. Role of insulin resistance in human disease (Banting lecture). Diabetes. 1988;37:1595-1601.
6. Egan BM, Stepniakowski KT. Evidence linking fatty acids, the risk factor cluster, and vascular pathophysiology: implications for the diabetic hypertensive patient. In: Sowers JR, ed. Diabetes and Vascular Disease. Tocowa, NJ: Humana Press; 1996:157-172.
7. Davda RK, Stepniakowski KT, Lu G, Ullian ME, Goodfriend TL, Egan BM. Oleic acid inhibits endothelial nitric oxide synthase by a protein kinase C-independent mechanism. Hypertension, 1995;26: 764-770.
8. Egan BM, Hennes MMI, O'Shaughnessy IM, Stepniakowski KT, Kissebah AH. Obesity hypertension is more closely related to impairment of insulin's fatty acid than glucose lowering action. Hypertension. 1996;27(pt2):723-728.
9. Chen YD, Golay A, Swislocki ALM, Reaven GM. Resistance to insulin suppression of plasma free fatty acid concentrations and insulin stimulation of glucose uptake in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab. 1987;64:17-21.
10. Jensen MD, Haymond MW, Rizza RA, Cryer PE, Miles JM. Influence of body fat distribution on free fatty acid metabolism in obesity. J Clin Invest. 1989;83:1168-1173.
11. Reaven GM, Hollenbeck C, Jeng CY, Wu MS, Chen YD. Measurement of plasma glucose, free fatty acid, lactate and insulin for 24 h in patients with NIDDM. Diabetes. 1988;37:1020-1024.
12. Roust LR, Jensen MD. Postprandial free fatty acid kinetics are abnormal in upper body obesity. Diabetes. 1993;42:1567-1573.
13. 2+ and phospholipids. J Biol Chem. 1986;261:15424-15429.
14. Khan WA, Blobe G, Halpern A, Taylor W, Wetsel WC, Burns D, Loomis C, Hannun YA. Selective regulation of protein kinase C isoenzymes by oleic acid in human platelets. J Biol Chem. 1993; 268:5063-5068.
15. Glatz JFC, York MM, Cistola DP, Van der Vusse GJ. Cytoplasmic fatty acid binding protein: significance for intracellular transport of fatty acids and putative role on signal transduction pathways. Prostaglandins Leukot Essent Fatty Acids. 1993;48:33-41.
16. Dzau VJ, Gibbons GH. Endothelium and growth factors in vascular remodeling of hypertension. Hypertension. 1991;18(suppl III):III-115-III-121.
17. Chamley-Campbell JH, Campbell GR, Ross R. The smooth muscle cell in culture. Physiol Rev. 1979;59:1-61.
18. Bradford M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-254.
19. Compton SJ, Jones CG. Mechanism of dye response and interference in the Bradford protein assay. Anal Biochem. 1985;151:369-374.
20. Neary JT, Norenberg LOB, Norenberg MD. Protein kinase C in primary astrocyte cultures: cytoplasmic localization and translocation by a phorbol ester. J Neurochem. 1988;50:1179-1184.
21. Neary JT, Norenberg LB, Norenberg MD. Calcium-activated, phospholipid-dependem protein kinase C substrates in primary culture of astrocyte. Brain Res. 1986;385:420-424.
22. Yong VW. Proliferation of human and moose astrocytes in vitro: signalling through the protein kinase C pathway. J Neurol Sci. 1992;111:92-103.
23. House C, Kemp BE. Protein kinase C contains a pseudosubstrate prototope in its regulatory domain. Science. 1987;238:1726-1728.
24. Koide H, Ogita K, Kikkawa U, Nishizuka Y. Isolation and characterization of the ε subspecies of protein kinase C from rat brain. Proc Natl Acad Sci U S A. 1992;89:1149-1153.
25. Kazanietz MG, Areces LB, Bahador A, Mischak H, Goodnight J, Mushinski JF, Blumberg PM, Characterization of ligand and substrate specificity for the calcium-dependent and calcium-independent protein kinase C isozymes. Mol Pharmacol. 1993;44:298-307.
26. Ostrowski J, Meier KE, Stanton TH, Smith LL, Bomsztyk K. Interferon-γ and interieukin-1α induce transient translocation of protein kinase C activity to membrane in a B lymphoid cell line. J Biol Chem. 1988;263:13786-13790.
27. Jones LG, Ella KM, Bradshaw CD, Cause KC, Dey M, Wisehart-Johnson AE, Spivey EC, Meier KE. Activation of mitogen-activated protein kinases and phospholipase D in A7r5 vascular smooth muscle cells. J Biol Chem. 1994;269:23790-23799.
28. Toullec D, Pianetti P, Coste H, Bellevergue P, Grand-Perret T, Ajakane M, Baudet V, Boissin P, Boursier E, Loriolle F, Duhamel L, Charon D, Kirilovsky J. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J Biol Chem. 1991;266:15771-15781.
29. Davis PD, Elliott LH, Harris W, Hill CH, Hurst SA, Keech E, Hari-Kumar MK, Lawton G, Nixon JS, Wilkinson SE. Inhibitors of protein kinase C, 2: substituted bisindolylmaleimides with improved potency and selectivity. J Med Chem. 1991;35:994-1001.
30. Gordge PC, Jonathan R. Inhibitors of protein kinase C. Cell Signal. 1994;6:871-882.
31. Blackshear PJ, Nairn AC, Kuo JF. Protein kinases 1988: a current perspective. FASEB J. 1988;2:2957-2969.
32. Blackshear PJ. Approaches to the study of protein kinase C involvement in signal transduction. Am J Med Sci. 1988;296:231-240.
33. Ways DK, Cook PP, Webster C, Parker PJ. Effect of phorbol esters on protein kinase C-ζ. J Biol Chem. 1992;267:4799-4805.
34. Fujihara M, Connolly N, Ito N, Suzuki T. Properties of protein kinase C isoforms (β, ε ζ) in a macrophage cell line (J774) and their roles in LPS-induced nitric oxide production. J Immunol. 1994;152:1898-1906.
35. Standaert ML, Cooper DR, Hernandez H. Arnold TP, Farese RV. Differential down-regulation of insulin-sensitive protein kinase C isoforms by 12-O-tetradeconylphorbol-13-acetate in rat adipocytes and BC3H-1 myocytes. Endocrinology. 1993;132:689-692.
36. Hug H, Sarre TF. Protein kinase C isoenzymes: divergence in signal transduction? J Biol Chem. 1993;291:320-343. Review.
37. 1/S inhibition. Exp Cell Res. 1993;208:311-320.
38. Crabos M, Imber R, Woodtli T, Fabbro D, Erne P. Different translocalion of three distinct PKC isoforms with tumor-promoting phorbol ester in human platelets. Biochem Biophys Res Commun. 1991;178:878-883.
39. Touny SE, Khan W, Hannun Y. Regulation of platelet protein kinase C by oleic acid. J Biol Chem. 1990;265:16437-16443.
40. Nakanishi H, Exton JH. Purification and characterization of the ζ isoform of protein kinase C. J Biol Chem. 1992;267:16347-16354.
41. Khan WA, Blobe GC, Hannun VA. Activation of protein kinase C by oleic acid. J Biol Chem. 1992;267:3605-3612.
42. Cobb MH, Boulton TG, Robbins DJ. Extracellular signal-regulated kinases. Cell Regul. 1991;2:965-978.
43. Davis RJ. The mitogen-activated protein kinase signal transduction pathway. J Biol Chem. 1993;268:14553-14556.
44. Yoshida K, Asaoka Y, Nishizuka Y. Platelet activation by simultaneous actions of diacylglycerol and unsaturated fatty acids. Proc Natl Acad Sci U S A. 1992;89:6443-6446.
45. Khan W, Touny SE, Hannun YA. Arachidonic and cis-unsaturated fatty acids induce selective platelet substrate phosphorylation through activation of cytosolic protein kinase C. FEBS Lett. 1991;292:98-102.
46. Hoshina S, Ueffing M, Weinstein IB. Growth factor-induced DNA synthesis in cells that overproduce protein kinase C. J Cell Physiol. 1990;145:262-267.
47. Krauss RS, Housey GM, Johnson MD, Weinstein IB. Disturbance in growth control and gene expression in c3 h/10t/2 cell line that stably overproduces protein kinase C. Oncogene. 1989;4:991-998.
48. Rao GN, Alexander RW, Runge MS. Linoleic acid and its metabolites, hydroperoxyoctadecadienoic acids, stimulate c-fos, c-jun, and c-myc mRNA expression, mitogen-activated protein kinase activation, and growth in rat aortic smooth muscle cells. J Clin Invest. 1995;96:842-847.
49. Postnov YV, Kravtsov GM, Orlov SN, Pokudin NI, Postnov IY, Kotelevtsev YV. Effect of protein kinase C activation on cytoskeleton and cation transport in human erythrocytes: reproduction of some membrane abnormalities revealed in essential hypertension. Hypertension. 1988;12:267-273.
50. Ordway RW, Singer JJ, Walsh JV. Direct regulation of ion channels by fatty acids. Trends Neurosci. 1991;14:96-100.
51. Bagdade JD. Disorders of carbohydrate and lipid metabolism in uremia. Nephron. 1975;14:153-162.
52. Stout RW. Insulin and atheroma: an update. Lancet. 1987;1: 1077-1079.