Peptide nucleic acid - Sequence specific recognition in cancer diagnostics and gene therapy

Archive of Oncology

Volumn 9, Issue 1, 2001, Pages 33-37

  Četojević Simin, Dragana ^a   Jakimov, Dimitar ^a   Mrdanović, Jasminka ^a   Bogdanović, Višnja ^a   Kojić, Vesna ^a   Andrijević, Ljiljana ^a   Bogdanović, Gordana ^a  

^a Institute of Oncology Sremska Kamenica   (Yugoslavia)

Author keywords

Gene Therapy; Neoplasms; Peptide Nucleic Acids

Indexed keywords

APTAMER; COMPLEMENTARY RNA; DNA; OLIGONUCLEOTIDE; PEPTIDE NUCLEIC ACID;

CANCER DIAGNOSIS; CANCER GENETICS; GENE TARGETING; GENE THERAPY; HUMAN; MOLECULE; NUCLEOTIDE SEQUENCE; REVIEW;

EID: 0035717985     PISSN: 03547310     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (18)

1. Antisense oligonucleotides: A systematic high-throughput approach to target validation and gene function determination
2. Triplex-directed modification of genes and gene activity
3. Peptide nucleic acids as therapeutic agents
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5. Applications of peptide nucleic acids
6. Rational recognition of nucleic acid sequences
7. Unusual DNA conformations
8. Chemoselective biosensors
9. Invasion of the CAG triplet repeats by a complementary peptide nucleic acid inhibits transcription of the androgen receptor and TATA-binding protein genes and correlates with refolding of an active nucleosome containing a unique AR gene sequence
10. Single-nucleotide polymorphism analysis by MALDITOF mass spectrometry
11. Sensitive detection of p53 gene mutations by a 'mutant enriched' PCR-SSCP technique
12. Facilitated detection of oncogene mutations from exfoliated tissue material by a PNA-mediated 'enriched PCR' protocol
13. The telomerase challenge - An unusual problem in drug discovery
14. In vitro transcriptional and translational block of the bcl-2 gene operated by peptide nucleic acid
15. Dihydrotestosterone as a selective cellular/nuclear localization vector for antigene peptide nucleic acid in prostatic carcinoma cells
16. RNA as a small-molecule drug target: Doubling the value of genomics
17. Theoretical and experimental approaches to design effective antisense oliginucleotides
18. The i-motif in nucleic acids